非编码RNA在高血压及其靶器官损害中的作用
1.湖南中医药大学,湖南 长沙 410208;
2.湖南中医药大学第一附属医院,湖南 长沙 410007
收稿日期: 2025-03-30
修回日期: 2025-09-11
录用日期: 2026-03-18
网络出版日期: 2026-03-19
基金资助
湖南省自然科学基金项目(2026JJ82082);湖南省教育厅资助科研项目(25B0355);2023年度湖南中医药大学校院联合基金项目(2023XYLH036);湖南省自然科学基金青年项目(2021JJ40417);湖南省创新性省份建设专项抗击新冠肺炎项目(2020SK3009);湖南省科技人才托举工程项目(2020TJ-N01);全国名老中医药专家陈新宇传承工作室建设项目(国中医药人教函[2022]75号)
The Role of Non-coding RNA in Hypertension and Its Target Organ Damage
Received date: 2025-03-30
Revised date: 2025-09-11
Accepted date: 2026-03-18
Online published: 2026-03-19
朱智显
,
陈新宇
,
姚昆鹏
,
彭丽琪
,
张小琴
.
非编码RNA在高血压及其靶器官损害中的作用
The incidence of hypertension is increasing year by year, and the target organ damage is obvious, can involve multiple organs at the same time. However, the early symptoms are not easy to detect, and most of them are diagnosed when there are clinical complications, which seriously threatens people's physical and mental health and brings a heavy burden to the social public health system. The pathogenesis of hypertension is complex and not fully understood, and there is a lack of effective and precise prevention and treatment measures. In recent years, non-coding RNA(nc RNA)has become a hot spot in the field of disease research, which plays an important regulatory role in the occurrence and development of tumor diseases, cardiovascular diseases, and nervous system diseases. This review focuses on the differential expression and mechanism of ncRNA in hypertension and target organ damage such as heart, kidney, and brain, and reveals its potential as a target for prevention and treatment.
Key words: Hypertension; Target organ damage; Non-coding RNA
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