The Evaluation Value of CALLY Index for Coronary
Artery Lesions and Prognosis in Children with Kawasaki Disease

doi:10.1009-0959.2026.030001

Abstract

Abstract:

Objective： To explore the evaluation value of indicators such as the CALLY index for the coronary artery lesions and prognosis in children with typical Kawasaki disease.Methods： A retrospective analysis was conducted on 287 children with typical Kawasaki disease （KD） who were treated at Hebei Children's Hospital from June 2021 to June 2025. Among them， there were 241 children without coronary artery lesions （CAL^-） and 46 children with CAL（CAL⁺，29 cases in the group with coronary artery recovery within 8 weeks of treatment and 17 cases in the group with persistent coronary artery dilation at 8 weeks of treatment）. The peripheral whole-blood routine， serum protein quantification， serum C-reactive protein and other indicators were detected to evaluate the indicative role of the above indicators in coronary artery lesions and their impact on prognosis.Results： In children with KD in the CAL⁺ group， the levels of lymphocytes （LYM）， serum albumin （ALB）， and the CALLY index were significantly lower than those in the CAL^-group， while the level of C-reactive protein （CRP） in the CAL⁺ group was significantly higher than that in the CAL^- group， and the differences were statistically significant （P<0.01）； Compared with the CAL^-group， the CAL⁺ 8-week continuous dilation group and the CAL⁺ recovery within 8 weeks group showed continuous reduction during the acute phase， clinical recovery phase， 4 weeks after IVIG treatment， 8 weeks after IVIG treatment and other periods. When comparing the CAL⁺ 8-week continuous dilation group with the CAL⁺ recovery within 8 weeks group， it was found that the reduction was more significant during the acute phase， clinical convalescence phase and 8 weeks after IVIG treatment （P<0.05）.Conclusion： The CALLY index can serve as a good early predictive indicator for the development of CAL in the acute phase of KD， and it plays a sensitive indicative role in the assessment of the prognosis of KD complicated with CAL.

Key words: CALLY index； , Kawasaki disease； , Children； , Coronary artery lesions； , Prognosis； , Evaluation value

CLC Number:

R725.4

GAO Hongliang, ZHANG Pengqian, ZHANG Xiaojuan, NIU Honglei, ZHANG Guiying, ZHAO Junshan.

The Evaluation Value of CALLY Index for Coronary Artery Lesions and Prognosis in Children with Kawasaki Disease [J]. CHINESE JOURNAL OF MEDICINAL GUIDE, 2026, 28(3): 250-255.

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The Evaluation Value of CALLY Index for Coronary Artery Lesions and Prognosis in Children with Kawasaki Disease

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