Research Progress on Traditional Chinese and Western Medicine Treatments for Post-Pulmonary Resection Cough

  • 笑雪 张
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  • 1.Heilongjiang University of Chinese Medicine Heilongjiang Harbin 150040, China
    2.The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine Heilongjiang Harbin 150001, China

Received date: 2025-04-22

  Revised date: 2025-08-04

  Accepted date: 2025-12-24

  Online published: 2025-12-24

Abstract

Post-pulmonary resection cough PPRC refers to persistent cough following thoracic surgery representing one of the most common postoperative complications. Based on clinical course it can be classified into subacute ≤8 weeks and refractory >8 weeks postoperative cough. This condition not only impedes postoperative recovery but also significantly compromises patients' quality of life imposing substantial psychological and economic burdens.The pathogenesis of PPRC remains incompletely understood with potential contributing factors including mediastinal lymph node dissection altered pulmonary anatomy and endotracheal intubation-related airway irritation. Western medicine treatment mainly empolays central antitussive agents which are limited by adverse effects abuse potential and suboptimal efficacy against refractory cases.Traditional Chinese Medicine TCM offers a unique theoretical framework and extensive clinical experience in cough management particularly for idiopathic refractory cases. TCM characterizes PPRC as a "deficiency-rooted excess-surface" syndrome. Through syndrome differentiation compound herbal formulations and patented Chinese medicines exert multi-target therapeutic effects while adjunctive techniques like acupuncture and acupoint application demonstrate notable clinical benefits. Current evidence suggests favorable safety profiles of TCM interventions though large-scale long-term pharmacovigilance studies are warranted.This review synthesizes recent 5-year advances in the mechanistic understanding and therapeutic strategies for PPRC from both western medicine and TCM perspectives aiming to provide evidence-based references for clinical decision-making.


Cite this article

笑雪 张 .

Research Progress on Traditional Chinese and Western Medicine Treatments for Post-Pulmonary Resection Cough

[J]. CHINESE JOURNAL OF MEDICINAL GUIDE, 2025 , 27(11) : 1149 -1149-1153 . DOI: magtech.2025.04.22-00002

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