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Clinical Study on Quantitative Evaluation of Coronary Lesions and Microcirculation in Patients with SCAD by CMR Perfusion Imaging
Received date: 2025-02-23
Revised date: 2025-09-10
Accepted date: 2025-12-24
Online published: 2025-12-24
Objective： To evaluate the quantitative evaluation value of cardiac magnetic resonance （CMR） perfusion imaging for coronary lesions and microcirculation in patients with stable coronary artery disease （SCAD）.Methods： 90 patients with SCAD admitted in our hospital from January 2023 to January 2024 were randomly selected. All patients received CMR perfusion imaging， and the diagnostic coincidence rate of CMR perfusion imaging in patients with SCAD was analyzed using the results of coronary angiography as the gold standard. The degree of coronary stenosis was evaluated according to the results of coronary angiography. Patients with mild to moderate stenosis （coronary stenosis rate ≤75%） were included in the mild to moderate group， and patients with severe stenosis （coronary stenosis rate >75%） were included in the severe group. The differences of CMR perfusion parameters in SCAD patients with different degrees of coronary stenosis were compared. Microcirculation disorder was evaluated according to the results of coronary angiography. Patients with microcirculation disorder were included in the disorder group and those without microcirculation disorder were included in the non-disorder group. The perfusion parameters of the two groups were compared.Results： There was no significant difference in the diagnosis coincidence rate of LAD， RCA and LCX by CMR perfusion imaging compared with coronary angiography （P>0.05）. Coronary angiography results showed that among the 90 patients with SCAD， 41 cases were mild to moderate stenosis and 49 cases were severe stenosis. The first pass perfusion time and myocardial delayed enhancement signal in the severe group were higher than those in the mild to moderate group， and slopemax was lower than that in the mild to moderate group （P<0.05）. In the 90 patients with SCAD， 24 had microcirculation disorder.The first pass perfusion time and myocardial delayed enhancement signal in the disorder group were higher than that in the non-disorder group， and slopemax was lower than that in the non-disordor group （P<0.05）.Conclusion： CMR perfusion imaging can accurately diagnose coronary artery lesions in patients with SCAD， and can quantitatively analyze coronary artery lesions and microcirculation disorders in patients with SCAD， providing certain reference for clinical evaluation of patients with SCAD.
YAN Jun, YANG Zhuoxuan
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Clinical Study on Quantitative Evaluation of
Coronary Lesions and Microcirculation in Patients with SCAD by CMR Perfusion
Imaging
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