氨基末端B型利钠肽对肺栓塞患者病情的估测价值

氨基末端B型利钠肽对肺栓塞患者病情的估测价值

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-02-25

The Evaluation Value of NT-proBNP in Pulmonary Thromboembolism Patient

Received:1900-01-01 Revised:1900-01-01 Online:2012-02-25

摘要/Abstract

摘要： 目的:探讨氨基末端B型利钠肽(NT-proBNP)在评价肺栓塞严重程度中的作用以及对肺栓塞患者病情的估测价值。方法:采用罗氏Elecsys2010电化学发光免疫分析仪对2009年1月～2010年4月期间在我院内科系统住院治疗的PTE患者及年龄与性别匹配的健康人群进行NT-proBNP测定,并用SPSS15.0软件包进行统计学处理。结果:非大面积PTE患者血清NT-proBNP水平与健康对照组间性比相比P>0.05,但次大面积及大面积PTE患者血清NT-proBNP水平要明显高于对照组及非大面积PTE组(P<0.01),且大面积PTE组NT-proBNP又明显高于次大面积PTE组(P<0.01)。结论:NT-proBNP的水平可以灵敏地反映PTE患者的栓塞面积及病情严重程度,是指导治疗的一项简便、灵敏的工具。

Abstract: Objective:To investigate the NT-proBNP function in severe degree of pulmonary thromboembolism(PTE) and the evaluation value of NT-proBNP in PTE patient.Methods:The NT-proBNP of PTE patients who were treated in hospital in the range of 2009.1-2010.4 and healthy people was analyzed on the Roche Elecsys 2010 electrochemistries analyze.The result was processed by SPSS 15.0.Results:The phase ratio of NT-proBNP result of in-large area PTE group and healthy controlled group was not different in statistics(P>0.05),but the NT-proBNP result of meta-large area PTE group and large area PTE group was higher than healthy controlled group and in-large area PTE group(P<0.01).Otherwise,the NT-proBNP result of large area PTE group and large area PTE group was higher than meta-large area PTE group(P<0.01).Conclusions:The level of NT-proBNP could sensitively reflect the embolism area and severe degree of PTE patient.It was a simple and sensitive tool to guide treatment.

. 氨基末端B型利钠肽对肺栓塞患者病情的估测价值[J]. .

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