Abstract: Objective:Minimally invasive percutaneous plate osteosynthesis is a new technique for internal fixation.The purpose of this paper was reported to discuss the clinical effects of treating by minimally invasive percutaneous locking plate osteosynthesis.Methods:Thirty-one patients of tibia fructure were treated by minimally invasive percutaneous plate osteosynthesis,20 patients for men and 11 patients for women.The average age of patients was 40.There were 12 patients for distal end fracture and 19 patients for proximal fracture.Based on the AO fracture classification,31 patients were divided into A in 26 patients,B in 3 patients,C in 2 patients.Results:All the patients were followed up for ten months.Except one for superficial infection and one for skin vesicle,all fractures were healed for one term without inlay bone and deformity union.The clinical heal time was between 12 and 24 weeks.The clicinal effect in near period were evaluated by Johner-Wruhs methods,best in 26 patients and good in 2 patients and middle in 3 patients and no poor.Conclusion:There are many advantages for minimally invasive percutaneous plate osteosynthesis,such as less trauma and less bleeding,and more stabilization as well as higher healing rate.Therefore,the technique has better effect.