Abstract: Objective:To analyze and evaluate the use of multiple hepatectomy operation treatment of complicated hepatolithiasis operation method,discusses how to improve operation effect and reduce the incidence of complications.Methods:In our hospital from 2002 October to 2010 December,71 cases of complex hepatolithiasis patients,using multiple hepatic resection operation for treatment,analysis and evaluation of multiple hepatic resection operation methods of clinical treatment effect.Results:The successful completion of intrahepatic bile duct stone removal operation in 52 cases,removal rate is 73.2%,the residual calculi in 19 cases,after 3 ～ 6 months through the T tube sinus endoscope of biliary tract stone 17 cases,net extraction in 15 cases,eventually the stone-free rate was 94.4%.Conclusion:The use of multiple hepatic resection operation in the treatment of complicated hepatolithiasis with respect to clinical outcome is satisfactory,but still cannot reduce operation complication.To ensure the smooth completion of multiple hepatic resection operation with respect to need to do the following: the involvement of range accurate assessment;judge the appropriateness of the hepatic resection types;try to maintain the normal liver tissues;the implementation of conventional choledochotomy and T tube drainage;to avoid accidental injury of intrahepatic normal tissue structure.