Abstract: Objective: To investigate the acute massive pulmonary thromboembolism clinical expression of cardiac troponin I levels and its significance.Methods:A retrospective analysis, selection in February 2013 to August 2014, our hospital for treatment of the clinical data of 120 patients with pulmonary thromboembolism, according to whether the patients with acute massive pulmonary embolism of 120 patients were divided into two groups, with as the observation group, patients with acute massive pulmonary embolism was associated with acute massive pulmonary embolism patients as control group, each group of 60 cases each.Using automatic biochemistry analyzer, ultrasonic instrument detection such as patients' serum myocardial enzyme, concentration of serum cardiac troponin I, pulmonary artery systolic blood pressure, blood gas, etc., and analysis in patients with acute massive pulmonary thromboembolism plasma cardiac troponin I in different times the value of the average values. Results: Through testing and analysis, found that in the control group in patients with myocardial troponin I measurements, right cardiac insufficiency, blood gas analysis, symptoms and prognosis results were significantly better than the observation group, the statistical comparison, P＜0.05, there was statistical significance; And observation group of patients with cardiac shock and mortality is significantly higher than the control group, by statistical comparison, P＜0.05, there was statistical significance; The observation group of patients with cardiac troponin I monitoring, found that patients with positive reaction after 5 h, peak after 20 h in patients with positive values.Conclusion:Patients with acute massive pulmonary thromboembolism myocardial troponin I level increased significantly, it is use as a judge index of lesions, is helpful for disease risk stratification, improve the prognosis of patients quality of life.