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急性心肌梗死患者收缩压水平与预后关系的探讨

耿学峰,宋丽萍,郭云飞,周淋   

  1. (北京市海淀医院心内科,北京 100080)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-06-25

Study on Relationship between Systolic Blood Pressure and Prognosis in Patients with Acute Myocardial Infarction

GengXue-feng,Song Li-ping,GuoYun-fei,et al.   

  1. (Department of Cardiology,Beijing Haidian Hospital,Beijing 100080, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2016-06-25

摘要: 【摘要】目的:探讨急性心肌梗死(AMI)患者入院时临床特征,收缩压水平及与预后的关系。方法:回顾性分析1257例急性心肌梗死患者资料,根据其入院时收缩压(SBP)水平而分为五组,分别比较各组的基本临床资料、冠状动脉造影结果和院内并发症及死亡率情况。结果:急性心肌梗死患者院内病死率为(<106mmHg)22.1%最高、其余分别是[(106~125)mmHg]5.4%、[(126~140)mmHg]4.9%、[(141~160)mmHg]2.9%和(>160mmHg)3.9%。患者入院时收缩压低于106mmHg组的的死亡率、心源性休克和肾功能不全发生率均高于其他四组。多因素Logistic回归分析显示,SBP<106mmHg(OR=2.671,P<0.05)和肌钙蛋白T峰值(OR=4.562,P<0.05)肾功能不全及冠状动脉多支和左主干病变是入院AMI患者死亡的独立危险因素。结论:入院时SBP<106mmHg患者在院期间病死率高,入院收缩压低可作为判断AMI患者预后不良的一个较好指标。

Abstract: 【ABSTRACT】Objective: To investigate the relationship between systolic blood pressure at admission and prognosis in patients with acute myocardial infarction (AMI).Methods:Data of 1257AMI patients admitted were retrospectively analyzed.Patients were classified into 5 groups according to the level of SBP at admission. The basic clinical data, the results of coronary angiography,complications and mortality of each group were compared.Results:A significantly higher mortality(22.1%) was found in Patients with SBP<106mmHg, The mortality,cardic shock andrenal insufficiency in patients with SBP<106mmHg were higher than those in other four groups.Multivariate logistic regression analysis demonstrated that SBP<106mmHg(OR=2.671, P<0.05) troponin T peak(OR=4.562,P<0.05), renal insufficiency, multivessel coronary artery and left main disease were independent positive predictors of hospital mortality.Conclusions:Higher mortality rate was found in AMI patients with SBP<106mmHg at admission,and lower SBP at admission can be used as a better indicator of poor prognosis in patients with AMI.