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卒中相关性肺炎的相关危险因素及预测因子分析

赵洋,刘强,张毅,靳传林,乔元元   

  1. 新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,济宁医学院附属医院
  • 收稿日期:2017-07-24 修回日期:2017-10-17 出版日期:2017-11-25

Analysis of the Risk Factors and Predictors Related to Stroke Associated Pneumonia

赵洋,liuqiang,张毅,靳传林 and qiaoyuanyaun   

  1. 新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,新疆维吾尔自治区职业病医院ICU,jinanyiyuan
  • Received:2017-07-24 Revised:2017-10-17 Online:2017-11-25

摘要: 目的:确定与卒中相关性肺炎(SAP)相关的危险因素及预测因子。方法:选取2012年1月至2016年6月我院自发病到住院7d内的914例患者作为研究对象,采用单变量和多变量Logistic回归分析对人口统计学、既往病史、NIHSS、OCSP、临床表现及症状、化验结果、住院时间、生活习惯等项目中24个可疑危险因素进行考察分析。结果:在914例合格患者中,所有患者的平均年龄(67.33± 11.62)岁,其中578例(63.28%)为男性,336例(36.76%)为女性,SAP患者在所有患者中所占比例为22.65%;单变量Logistic回归分析确定了年龄、吞咽困难、房颤、糖尿病、中风史、TIA史、昏迷、抑酸剂、鼻饲置管、抗生素、NIHSS评分、LACI、PACI、TACI、POCI、CRP、PCT、住院时间共18个因素为SAP危险因素;多变量Logistic回归分析发现,年龄、吞咽困难、糖尿病、抑酸剂、NIHSS评分、TACI、CRP、PCT、住院时间共9个因素与SAP显著相关。结论:本研究中18个危险因素应受到医生和患者的重视,患者入院时吞咽困难、TACI、CRP和PCT等症状和项目同时可作为SAP的预测因子。

Abstract: Objective: To identify the risk factors and predictive factors related to stroke associated pneumonia(SAP). Methods: 914 cases of patients which treated in our hospital and admitted within 7d from onset to hospital during January 2012 to June 2016 were as the objects of study. A total of 24 suspected risk factors, including demographics, anamnesis, NIHSS, OCSP, clinical manifestations and symptoms, test results, hospitalization time and living habits were analyzed by univariate and multivariate logistic regression analysis. Results: Among the 914 eligible patients, the mean age of all patients was (67.33±11.62) years, 578(63.28%) were male and 336(36.76%) were female, and the proportion of SAP patients was 22.65% in all patients. Univariate logistic regression analysis showed that 18 factors were risk factors for SAP such as age, dysphagia, atrial fibrillation, diabetes mellitus, stroke history, TIA history, coma, antacid, nasal feeding, antibiotics, NIHSS score, LACI, PACI, TACI, POCI, CRP, PCT and hospitalization time. Multivariate logistic regression analysis indicated that 9 factors(age, dysphagia, diabetes, antacid, NIHSS score, TACI, CRP, PCT, and hospitalization time) were significantly associated with SAP. Conclusion: 18 risk factors in this study should be addressed by physicians and patients, dysphagia, TACI, CRP, PCT and other symptoms and project of patients at admission could be used as the predictors of SAP.