Abstract: Objective：To compare the disposable injection apparatus product transport different leaching effect of provided methods for the solution of the pyrogen detection.Methods： According to the experimental principle of GB/T14233.2-2005 and GB/T16886.12-2005，the product of 4 different varieties of different specifications of 58 batches of different types of production enterprises were tested with thermal original. Results： 58 batches of different specifications of disposable infusion apparatus is leaching solution with 0.9% sodium chloride injection， according to the 0.2 g： 1 mL 121 ℃ heat preservation for 1 h， according to the rabbit injected 10 mL per kilogram weight， rabbit pyrogen inspection results are less than 0.6 ℃ temperature warming； disposable infusion apparatus with batch products with 0.9% sodium chloride injection for leaching solution extraction to 37 ℃ nominal capacity of heat preservation for 24 h， according to the injected 10 mL per kilogram weight on rabbit， rabbit pyrogen inspection results are less than 0.6 ℃ temperature warming. Samples from 58 batches of 4 different varieties were sampled from 3 batches to contain 10 EU·mL-1 bacterial endotoxin 0. 9% sodium chloride injection for leaching medium， according to the 0.2 g： 1 mL 121 ℃ heat preservation for 1 h， according to the rabbit injected 10 mL per kilogram weight， rabbit pyrogen inspection results are less than 0.6 ℃ temperature warming； the product of the infusion device was used in the same batches to contain 10 EU·mL-1 bacterial endotoxin 0. 9% sodium chloride injection extraction to 37 ℃ nominal capacity of heat preservation for 24 h，according to the injected 10 mL per kilogram weight on rabbit， rabbit pyrogen test results for each group(3 group only) temperature rising at least one greater than 0.6 ℃.Conclusion： When the temperature rises， it may lead to leaching of pyrogens reduced，thus affecting the pyrogen test.