体外受精-胚胎移植后发生异位妊娠34例临床分析

体外受精-胚胎移植后发生异位妊娠34例临床分析

邹宇洁,尹太郎,杨菁,高玥,常硕

武汉大学人民医院,武汉大学人民医院,武汉大学人民医院,武汉大学人民医院,武汉大学人民医院

收稿日期:2017-09-10 修回日期:2017-11-29 出版日期:2017-12-25
基金资助:
湖北省自然科学基金资助项目(项目编号：2016CFB352；项目名称：用于少弱精子无保护剂超快速冷冻的新型微流控芯片研究)；湖北省卫计委面上项目(项目编号：WJ2017M011；项目名称：乙酰左旋肉碱在人精子冷冻过程中的抗氧化损伤作用及机制研究)

Clinical Analysis of 34 Cases of Ectopic Pregnancy after in vitro Fertilization and Embryo Transfer

zouyujie,yintailang,yangjing,gaoyue and changshuo

renmin Hospital，wuhan university,renmin Hospital，wuhan university,renmin Hospital，wuhan university,renmin Hospital，wuhan university,renmin Hospital，wuhan university

Received:2017-09-10 Revised:2017-11-29 Online:2017-12-25

摘要/Abstract

摘要： 目的：探讨体外受精-胚胎移植（IVF-ET）后异位妊娠的发生率、相关因素及诊疗方法。方法：回顾性分析IVF-ET后发生异位妊娠34例的临床资料。结果：1 140例临床妊娠中，宫内妊娠1 106例，异位妊娠34例(2.98%)，包括宫内外同时妊娠5例。输卵管因素不孕异位妊娠的发生率为4.4%（27/619），远高于因子宫内膜异位症、排卵障碍等因素异位妊娠的发生率。年龄、受精方式、胚胎来源和移植次数对异位妊娠的发生率无明显影响。结论：IVF-ET后异位妊娠发生率较自然妊娠时高，而输卵管病变是影响IVF-ET后异位妊娠发生率的主要因素。妊娠早期通过血HCG和B超监测，有助于异位妊娠的早诊断和早治疗。

Abstract: Objective： To study the incidence， risk factors and clinical manifestation for ectopic pregnancy after in vitro fertilization and embryo transfer (IVF-ET). Methods： Retrospective study of 34 cases of ectopic pregnancy after IVF-ET. Results： Of 1 140 clinical pregnancy， there were 1 106 intrauterine pregnancy and 34 ectopic pregnancy(2.98%)， including 5 heterotopic pregnancy. The incidence of ectopic pregnancy in tubal factor group was 4.4%(27/619)， higher than that of other factors. There was no correlation between age， fertilization way， source of embryo， transplantation times and ectopic pregnancy. Conclusion： Incidence of ectopic pregnancy after IVF-ET is higher than that of natural pregnancy， with tubal factors to be the closely related. Early measurement of blood HCG and B ultrasound contribute to the early diagnosis and treatment of ectopic pregnancy.

邹宇洁,尹太郎,杨菁,高玥,常硕. 体外受精-胚胎移植后发生异位妊娠34例临床分析[J]. .

zouyujie,yintailang,yangjing,gaoyue and changshuo. Clinical Analysis of 34 Cases of Ectopic Pregnancy after in vitro Fertilization and Embryo Transfer[J]. .

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