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艾滋病合并结核性脑膜炎114例临床分析

罗江萍,董玉洁,舒占钧,杨彤彤,王静,蒋程媛,鲍刚   

  1. 深圳罗湖区人民医院,新疆维吾尔自治区第六人民医院,新疆维吾尔自治区第六人民医院,新疆维吾尔自治区第六人民医院,新疆维吾尔自治区第六人民医院,新疆维吾尔自治区第六人民医院,新疆维吾尔自治区第六人民医院
  • 收稿日期:2017-11-06 修回日期:2017-11-06 出版日期:2017-12-25
  • 基金资助:
    新疆维吾尔自治区卫生计生委青年科技人才科研项目(项目编号:2015Y33;项目名称:艾滋病合并结核性脑膜炎患者脑脊液置换及鞘内注射疗效观察);新疆维吾尔自治区第六人民医院院内课题(项目编号:QLY-kyht-2015;项目名称:艾滋病合并结核性脑膜炎患者脑脊液置换及鞘内注射疗效观察)

Clinical Analysis of 114 cases of AIDS Combined with Tuberculous Meningitis

LUO jiangping,DONG Yujie,SHU Zhanjun,YANG Tongtong,WANG Jing,JIANG Chenyuan and BAO Gang   

  1. Luohu District People′s Hospital of Shenzhen,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region,The Sixth People′s Hospital of Xinjiang Uygur Autonomous Region
  • Received:2017-11-06 Revised:2017-11-06 Online:2017-12-25

摘要: 目的:分析总结艾滋病(AIDS)合并结核性脑膜炎双重感染患者的临床资料,以期为临床治疗提供参考依据。方法:回顾性分析我院住院的AIDS合并结核性脑膜炎114例患者的临床资料。结果: AIDS合并结核性脑膜炎双重感染患者可出现头痛、恶心、呕吐、乏力、发热等临床表现,还可表现为精神异常及意识障碍,常合并肺结核及肺外结核表现,脑脊液压力多升高,脑脊液多表现为典型的结核性脑脊液生化特点。结论:AIDS合并结核性脑膜炎患者临床表现复杂,病死率高,CD4+小于200个·mm-3者较为常见,对可疑患者应尽早完善相关检查,及早诊断和治疗。

Abstract: Objective:To analyze and summarize the clinical data of double infection of AIDS combined with tuberculous meningitis, and to provide reference for clinical treatment.Methods: The clinical data of 114 cases of AIDS combined with tuberculous meningitis in our hospital were analyzed retrospectively.Results:AIDS combined with tuberculous meningitis caused headache, nausea, vomiting, fatigue and fever and other clinical manifestations. It could also be manifested as mental disorders and disturbance of consciousness.The manifestations of tuberculosis and pulmonary tuberculosis were often merged, the pressure of cerebrospinal fluid increased and the cerebrospinal fluid was characterized by the typical biochemical characteristics of tuberculous cerebrospinal fluid. Conclusion:The clinical manifestations of AIDS combined with tuberculous meningitis are complex and the mortality is high.CD4+ less than 200·mm-3 is more common,the suspicious patients should be done relevant examination as soon as possible,and early diagnosed and treated.