Abstract: Objective： To discuss neonatal safety of breast feeding when parturient women taking labetalol， give reference to rational use of drug and breast feeding. Methods：120 newborn infants who were born during October 2016 to July 2017 were chosen as examples and separated into two groups in proportion of 1∶1 and each group has 60 examples. The observation group was for infants and parturient women with gestational hypertension who continued taking labetalol. The control group was for healthy infants and parturient women who never took any medical treatments during the day. Infants′ clinical conditions in each group were observed. Results： The newborn infants in these two groups were comparable. In the two groups， infants′ blood pressure and heart rate were examined before beast feeding， 24h and 48h after breast feeding. Before and after breast feeding， the abnormal condition of blood routine， liver and renal function and the rate of jaundice appearance and regression were also examined. Compared with the control group， the differences of the results were not statistically significant (P>0.05). All the newborn infants in the observation group didn′t have adverse reaction such as hyperidrosis， poor response， gastrointestinal discomfort， rash， quicken respiration etc. 7d after drug withdrawal and 28d after delivery， there was not abnormal. Conclusion：There are no bad influences for newborn infants if parturient women with gestational hypertension takes labetalol when breast feeding， it is no need to restrict lactaion. Further pertinence studies on premature infants are needed.