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细菌耐药性与抗生素的合理使用探究

杜闻杉,王瑞,孙晓迪,王苏会,李志平,王春红,吴娟,李秀敏   

  1. 陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科,陆军总医院药剂科
  • 收稿日期:2017-06-21 修回日期:2018-03-02 出版日期:2018-03-25

Bacterial Resistance and the Rational Use of Antibiotics

DU Wen-shan,WANG Rui,SUN Xiao-di,WANG Su-hui,LI ZHi-ping,WANG CHun-hong,WU Juan and LI Xiu-min   

  1. Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army,Institute Department of Pharmacy,General Hospital of Army
  • Received:2017-06-21 Revised:2018-03-02 Online:2018-03-25

摘要: 抗生素的发现使细菌感染性疾病得到了有效的治疗和控制,但抗生素的不合理应用,导致细菌耐药和临床抗菌治疗失败,目前抗生素耐药性问题也已成为全球关注的焦点。为提高抗菌药物的治疗效果,减少细菌抗药性的产生,提高对感染性疾病的治疗效果,本文就感染性疾病的抗生素抑菌机理、细菌的耐药机制以及抗生素的合理使用等方面进行综述。

Abstract: The discovery of antibiotics make the bacterial infectious diseases received effective treatment and control, but the unreasonable application of antibiotics lead to bacterial resistance and clinical antibiotic treatment failure. The problem of antibiotic resistance become the focus of global attention. In order to improve the treatment effect of antibacterial agents and reduce the occurance of bacterial resistance, the antibacterial mechanism of antibiotics, bacterial resistance mechanisms and rational use of antibiotics and so on are summarized in this paper.