34例医务人员放射性甲状腺疾病临床特征分析

34例医务人员放射性甲状腺疾病临床特征分析

应可明,陈峥,燕归如,孙民昌,汤进,郑春梅,乔永峰,阚炳华

陕西省汉中市中心医院,陕西省汉中市中心医院,汉中市中心医院肿瘤外科,汉中市中心医院肿瘤外科,汉中市中心医院检验科,汉中市中心医院检验科,汉中市中心医院检验科,汉中市中心医院肿瘤外科

收稿日期:2018-03-27 修回日期:2018-05-25 出版日期:2018-05-25
基金资助:
陕西省汉中市科技局立项(项目编号：汉市科〔2015〕第19号；项目名称：放射性甲状腺癌与慢性放射性甲状腺炎的相关问题研究)；陕西省科学技术成果（成果登记号：9612015Y2697；成果名称：放射性甲状腺癌与慢性放射性甲状腺炎的相关问题研究）

Clinical Characteristics Analysis of 34 Cases of Radiation Thyroid Diseases of Medical Personnel

YING Keming,CHEN Zheng,YAN Guiru,SUN Minchang,TANG Jin,ZHENG Chunmei,QIAO Yongfeng and KAN Binghua

hanzhong center hospital,hanzhong center hospital,汉中市中心医院肿瘤外科,汉中市中心医院肿瘤外科,汉中市中心医院检验科,汉中市中心医院检验科,汉中市中心医院检验科,汉中市中心医院肿瘤外科

Received:2018-03-27 Revised:2018-05-25 Online:2018-05-25

摘要/Abstract

摘要： 目的：探讨分析介入放射医务人员放射性甲状腺疾病的临床病理资料，以期为临床诊断、治疗及职业防护提供参考依据。方法：回顾分析我院肿瘤外科2011年6月至2016年12月收治的34例放射性甲状腺癌与慢性放射性甲状腺炎患者的临床病理资料，依据国家制定的最新诊断标准进行分析探讨。结果：3例患者术后病理类型为甲状腺乳头状癌合并慢性淋巴细胞性甲状腺炎，1例患者术后病理类型为甲状腺乳头状癌合并结节性甲状腺肿；依据最新诊断标准，4例患者均诊断为放射性甲状腺癌合并慢性放射性甲状腺炎，30例患者仅诊断为慢性放射性甲状腺炎；慢性放射性甲状腺炎患者的甲状腺吸收放射线剂量与潜伏期的相关系数r=0.076，P=0.000，差异有统计学意义（P<0.01）。结论：目前尚未发现除甲状腺乳头状癌以外的放射性甲状腺癌的病理类型；不仅慢性淋巴细胞性甲状腺炎是慢性放射性甲状腺炎的一种病理类型，结节性甲状腺肿也可能是慢性放射性甲状腺炎的一种病理类型；不仅放射性甲状腺癌的发病率与甲状腺吸收放射线剂量、潜伏期呈显著的正相关，放射性甲状腺炎的发病率与甲状腺吸收放射线剂量、潜伏期也呈显著的正相关。

Abstract: Objective：To explore and analyze the clinicopathological data of radiation thyroid diseases in medical personnel for providing references for clinical diagnosis， treatment and occupational protection. Methods：The clinical data of 34 cases of radioactive thyroid cancer and chronic radiation thyroiditis in our hospital from June 2011 to December 2016 were retrospectively analyzed according to the latest diagnostic criteria. Results：The postoperative pathological types of 3 patients was considered as papillary thyroid cancer combined with chronic lymphocytic thyroiditis and 1 patient was regarded as papillary thyroid cancer combined with nodular goiter. According to the latest diagnostic criteria， 4 cases were diagnosed as radioactive thyroid cancer combined with chronic radiation thyroiditis and 30 patients were only diagnosed as chronic radiation thyroiditis. The correlation coefficient （r=0.076， P=0.000） between the doses which thyroid absorbed the radiation and latency in patients who suffered from chronic radiation thyroiditis was statistical significant(P<0.01). Conclusion：At present， except for thyroid papillary carcinoma， other pathological types of radioactive thyroid cancer have not been found. Not only is chronic lymphocytic thyroiditis a pathological type of chronic radioactive thyroiditis， but also nodular goiter may also be another pathological type of chronic radioactive thyroiditis. Not only is the incidence of radioactive thyroid cancer significantly positively correlated with the dose of radiation absorbed by the thyroid and latency in patients who suffered from radiation thyroid cancer， but also the incidence of chronic radiation thyroiditis is significantly positively related with the dose of radiation absorbed by the thyroid and latency in patients who suffered from chronic radiation thyroiditis.

应可明,陈峥,燕归如,孙民昌,汤进,郑春梅,乔永峰,阚炳华. 34例医务人员放射性甲状腺疾病临床特征分析[J]. .

YING Keming,CHEN Zheng,YAN Guiru,SUN Minchang,TANG Jin,ZHENG Chunmei,QIAO Yongfeng and KAN Binghua. Clinical Characteristics Analysis of 34 Cases of Radiation Thyroid Diseases of Medical Personnel[J]. .

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