Abstract: Objective：To study the effects of amino acid peritoneal dialysis on dialysis efficiency and nutritional status of continuous ambulatory peritoneal dialysis(CAPD)patients. Methods：21 cases of CAPD patients were treated with self-made amino acid peritoneal dialysis fluid.The patients were given three bags of normal peritoneal dialysis solution during the day，and amino acid peritoneal dialysis solution at night for about 8 h， and the changes of biochemical indexes such as urea nitrogen(BUN)，creatinine(Cr)，uric acid (UA)，serum albumin(ALB)， haemoglobin(HB)，serum calcium (Ca) and blood phosphorus (P) of CAPD patients and the occurrence of adverse reactions were observed for 8 weeks. Results：The osmotic pressure of 1.5% peritoneal dialysis solution was 341 mOsm/kg·H2O， after adding compound amino acid injection， the osmotic pressure increased from 365 to 379 mOsm/kg·H2O， similar to the osmotic pressure of 2.5% peritoneal dialysis solution， but the dialysis dehydration was higher than that of 1.5% and 2.5% peritoneal dialysis solution. After treated with amino acid peritoneal dialysis solution for 8 weeks， the ALB levels of the patients were increased from （27.49±3.82） g·L-1 to （28.64±4.41） g·L-1(P<0.05). Most patients have elevated levels of ALB， and the highest increase was about 8 g·L-1.The levels of blood BUN， UA and P of the patients were all decreased (P<0.05)，the levels of HB were increased (P<0.05)， but the levels of serum Cr and Ca did not changed significantly， the difference was not statistically significant (P>0.05). During the treatment， 5 patients had transient nausea and vomiting. No abdominal pain， diarrhea and peritonitis were observed.Conclusion：Amino acid peritoneal dialysis can increase dialysis efficiency and improve nutritional status of CAPD patients，and there was no obvious side effects.