T2WI FLAIR增强及减影技术在病毒性脑膜炎中的诊断价值

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T2WI FLAIR增强及减影技术在病毒性脑膜炎中的诊断价值

吴冬,赵志清,郑锐标,莫金潮,专庆春,吕永革,王俊国,钟金兰,余深平

深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,深圳市宝安区沙井人民医院,中山大学附属第一医院放射科

收稿日期:2018-12-25 修回日期:2019-02-21 出版日期:2019-03-25
基金资助:
深圳市宝安区科技局科技计划资助项目(项目编号：2017JD108；项目名称：磁化转移技术在提高3D-TOF-MRA图像质量中的应用研究)

Diagnostic Value of T2WI FLAIR Enhancement and Subtraction Technique in Viral Meningitis

WU Dong,ZHAO Zhiqing,ZHENG Ruibiao,MO Jinchao,ZHUAN Qingchun,LV Yongge,WANG Junguo,ZHONG Jinlan and YU Shenping

Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,Shajing People`s Hospital,Bao`an District,Shenzhen City,First Affiliated Hospital of Zhongshan University

Received:2018-12-25 Revised:2019-02-21 Online:2019-03-25

摘要/Abstract

摘要： 目的：评价MRI增强T2WI FLAIR序列在病毒性脑膜炎诊断中的意义及临床应用价值。方法：回顾性分析我院2015年1月至2018年9月经临床确诊的27例病毒性脑膜炎患者的影像资料，其中男性15例，女性12例，年龄13～58岁，平均年龄（31.52±5.37）岁。主要临床表现有发热24例，头痛23例。结果：病毒性脑膜炎T2WI FLAIR序列多表现为脑沟、裂、池信号增高，增强后表现为软脑膜或硬脑膜的均匀强化，多为脑回样、环状强化。27例脑膜炎患者中T2WI FLAIR增强上显示病变强化者有22例，在增强T1WI图像上显示病变强化者有15例，两者检出正确率差异有统计学意义(χ2=4.523，P=0.04)。结论：增强T2WI FLAIR 序列对于病毒性脑膜炎的显示具有较高的诊断准确性，同时，具有早期诊断病毒性脑膜炎病变的潜在价值。

Abstract: ]Objective：To evaluate the clinical value of MRI enhanced T2WI FLAIR sequence in the diagnosis of viral meningitis. Methods： The imaging data of 27 patients with viral meningitis in our hospital from January 2015 to September 2018 were retrospectively analyzed， including 15 males and 12 females， aged 13-58 years with an average age of（31.52±5.37）years. The main clinical manifestations were fever in 24 cases and headache in 23 cases. Results： The T2WI FLAIR sequence of viral meningitis was characterized by increased signal in the sulcus， fissures and cisterns. The enhancement was manifested as homogeneous enhancement of pia mater or dura mater， gyrus and ring enhancement. 22 of 27 patients with meningitis showed enhancement on T2WI FLAIR and 15 on T1WI .The difference was statistically significant (χ2=4.523， P=0.04). Conclusion： Enhanced T2WI FLAIR sequence has high diagnostic accuracy for viral meningitis， and has potential value for early diagnosis of viral meningitis lesions.

吴冬,赵志清,郑锐标,莫金潮,专庆春,吕永革,王俊国,钟金兰,余深平. T2WI FLAIR增强及减影技术在病毒性脑膜炎中的诊断价值[J]. .

WU Dong,ZHAO Zhiqing,ZHENG Ruibiao,MO Jinchao,ZHUAN Qingchun,LV Yongge,WANG Junguo,ZHONG Jinlan and YU Shenping. Diagnostic Value of T2WI FLAIR Enhancement and Subtraction Technique in Viral Meningitis[J]. .

参考文献

[1]张艳丽,孙晓琳,武军,等.TNF-α联合FLAIR序列对新生儿化脓性脑膜炎的诊断价值[J].中国妇幼健康研究,2017,28(11):1351-1353+1376.
[2]尹燕,李君伟,李璐,等.3D T2-FLAIR增强在儿童感染性脑膜炎诊断中的应用研究[J].医疗装备,2015,28(13):9-12.
[3]马力,苏国华,陈路宁,等.结核性脑膜炎MRI增强扫描的诊断价值[J].中国社区医师,2013,15(24):84.
[4]郭德松.磁共振快速FLAIR技术在结核性脑膜炎中的应用[J].中国卫生产业,2013,10(30):151-152.
[5] SPLENDIANI A,PUGLIELLI E,DE AMICIS Ｒ,et al．Contrast-enhanced　FLAIＲ in the early diagnosis of infectious meningitis[J]．Neuroradiology,2005,47( 8) : 591 －598．
[6]何俊瑛,张楠,李玉静,等.磁共振成像及脑脊液细胞学对病毒性脑(膜)炎的诊断性研究[J].中国现代神经疾病杂志,2011,11(05):538-542.
[7]揭冰,江森,孙希文,等.磁共振增强后液体衰减反转恢复序列在结核性脑膜炎诊断中的应用[J].中华临床医师杂志(电子版),2011,5(17):5100-5103.
[8] Parmar H, Sit oh YY, Anand P, et al. Contrast-enhanced FLAIR imaging in the evaluation of infect ious lept omeningeal diseases[J] .Eur J Radiol, 2006, 58(1):89-95.
[9] 董险峰,朱峰,张振明,张玉玲,张海燕,高志刚.CT、MRI在硬脑膜炎中的临床应用诊断价值[J].中国医药导刊,2013,15(03):394-395.
[10] 申小明,叶滨宾．增强T2WI-FLAIＲ对脑膜病变的诊断价值[J]．临床诊断及介入放射学,2010,19( 5) : 316－319．
[11]李红,马林,苏家贵,等.磁共振增强减影技术在结核性脑膜炎中的运用[J].中国医学影像技术,2007(02):194-197.
[12] Oguz KK,Cil AA． Rim enhancement of meningiomas on fast FLAIR imaging[J]．Neuroradiology,2003,45(2)：78-81．
[13]王东超.论CT、MRI对小儿病毒性脑膜炎中的价值分析[J].中国卫生产业,2013,10(30):117+119.
[14]陈静,李欣,王春祥,等.MR增强FLAIR和T_1WI序列对儿童感染性脑膜炎成像效能的对比[J].放射学实践,2010,25(12):1319-1322.
[15]邵艳敏,武文娟,张育德.动态观察脑脊液细胞学及生化指标结合MRI影像学诊断结核性脑膜炎的价值[J].中国CT和MRI杂志,2018,16(08):25-28.
[16]陈静,李欣,王春祥,赵滨.MR增强FLAIR和T1WI序列对儿童感染性脑膜炎成像效能的对比[J].放射学实践,2010,25(12):1319-1322.
[17]郁冰冰,姜庆军,李杰,朱明.动态增强MR数字减影技术在脑膜炎诊断中的应用[J].实用医药杂志,2010,27(09):806-807.
[18]江新青,彭国晖,辜金莲,彭仁罗.结核性脑膜炎的磁共振成像诊断[J].神经疾病与精神卫生,2001,8(04):34-35.
[19] 张丽艳,董险峰,张振明,朱峰,张海燕,张玉玲,高志刚.CT、MRI在耳源性脑膜炎的临床诊断与治疗分析上的应用[J].中国医药导刊,2013,15(01):58+60.
[20]向成燕,梁志鹏,张俊,胡家海.真菌性脑膜炎与颅内真菌性肉芽肿的CT和MR表现特点分析[J].中国医学装备,2018,15(10):51-54.

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