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中国医药导刊 ›› 2023, Vol. 25 ›› Issue (6): 586-591.

• 中医中药 • 上一篇    下一篇

八珍汤治疗老年髋部骨折围手术期贫血的理论分析与应用研究

常育豪1, 王会超2, 刘又文2*   

  1. 1.河南中医药大学, 河南 洛阳 471002;
    2.洛阳正骨医院(河南省骨科医院)髋部损伤二科, 河南 洛阳 471002
  • 收稿日期:2023-01-18 修回日期:2023-03-20 出版日期:2023-06-28 发布日期:2023-06-28
  • 基金资助:
    国家自然科学基金面上项目(项目编号:82074472;项目名称:基于TLR4/MyD88/NF-κB信号通路探讨补肾活血法促M2极化干预激素性股骨头坏死的骨免疫机制);2021年洛阳市科技计划医疗卫生专项(项目编号:2101072A;项目名称:补益气血方联合氨甲环酸在老年股骨转子间骨折患者围术期血液管理中的应用)

Theoretical Analysis and Application of Bazhen Decoction in the Treatment of Perioperative Anemia in Elderly Patients with Hip Fracture

  1. 1.Henan University of Chinese Medicine, Henan Luoyang 471002, China;
    2.Department of Hip Injury, Luoyang Orthopedic-Traumatological Hospital of Henan Province (Henan Provincial Orthopedic Hospital),Henan Luoyang 471002, China
  • Received:2023-01-18 Revised:2023-03-20 Online:2023-06-28 Published:2023-06-28
  • Contact: You-Wen -LIU E-mail:liuyouwen543@sina.com

摘要: 近年来,老年髋部骨折患者的数量不断增加。作为老年髋部骨折患者所面对的主要并发症,围手术期贫血的治疗值得关注。八珍汤是中医治疗气血亏虚的经验名方,长久以来用于治疗各种气血两虚证。八珍汤及其加减方,可有效改善老年髋部骨折围手术期贫血患者临床症状,提高生活质量,且具有良好的安全性,疗效确切。其作用机制与调节神经内分泌因子、影响免疫调节,抑制细胞凋亡,最终促进造血有关。本研究从理论、临床以及实验等方面阐释八珍汤治疗老年髋部骨折围手术期贫血的研究进展,阐释八珍汤在治疗本病的应用现状并对未来发展方向加以思考。在病证结合原则指导下,以证候研究为突破口,以期揭示八珍汤的综合疗效机制,精准把握其临床应用并提高其疗效。

关键词: font-size:medium, ">八珍汤;老年髋部骨折;围手术期贫血;理论研究;临床研究;实验研究

Abstract: In recent years, the number of elderly patients with hip fractures is increasing. As a major complication faced by elderly hip fracture patients, the treatment of perioperative anemia deserves attention. Bazhen decoction is an experienced and famous prescription for treating Qi and blood deficiency in traditional Chinese medicine. It has been used to treat various Qi and blood deficiency syndrome for a long time. Bazhen decoction and its modified formula can effectively improve the clinical symptoms and quality of life of elderly hip fracture patients with perioperative anemia, and has good safety and definite efficacy. Its mechanism of action is related to regulating neuroendocrine factors, affecting immune regulation, inhibiting apoptosis, and ultimately promoting hematopoiesis. This study reviewed the research progress of Bazhen decoction in the treatment of perioperative anemia of elderly hip fracture patients from theoretical, clinical and experimental aspects, explained the application status of Bazhen decoction in the treatment of this disease and thought about the future development direction. Under the guidance principle of combining disease and syndrome, the study of syndromes is expected to reveal the comprehensive therapeutic mechanism of Bazhen decoction, accurately grasp its clinical application and improve its therapeutic effect.

Key words: font-size:medium, ">Bazhen Decoction; Hip fracture in the elderly; Perioperative anemia; Theoretical study; Clinical studies; Experimental study

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