Abstract: Objective：To investigate the effect of sevoflurane and isoflurane inhaled anesthetics of 1.3 times MAC inhalation on the rate of rocuronium continuous infusion during the operation of children. Methods：A total of 90 cases of children admitted in our hospital to undergo the general anesthesia surgery from February 2016 to April 2017 were randomly divided into study group 1， study group 2 and control group. These three groups of patients were anesthetized with propofol， rocuronium was administrated for the amount of 0.6 mg·kg-1 in intravenous infusion and tracheal intubation， and during the infusion process， wrist ulnar nerve was given stimulation for 4 consecutive times using muscle relaxation monitor. Times for fingers muscle convulsion were recorded and their occurrence times were T1， T2， T3， T4. Rocuronium could be used under the condition that T1 returned to 5% original dose， and during the process， T1 was maintained at about 9% by adjusting the infusion rate. If T1 was stable within 5 min， the infusion rate would be adjusted to the initial rate. Study 1 group， study 2 group and control group inhaled sevoflurane， isoflurane and propofol respectively， and the dosage amount should ensure that the end expiratory concentration was at about 1.3 MAC. The variation of rocuronium infusion rate was compared between the three groups after 10， 20 and 30 min， and the incidence of adverse reaction was compared as well. Results：Comparison of rocuronium infusion rate between three groups was study group 2