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胱抑素C与类风湿关节炎心血管病变

薛晓倩,江洪耿,薛文昌   

  1. 揭阳市人民医院,揭阳市人民医院,揭阳市榕城区慢性病防治院
  • 收稿日期:2018-07-18 修回日期:2018-11-11 出版日期:2018-12-25
  • 基金资助:
    揭阳市医学科学技术研究项目(课题名称:同型半胱氨酸、胱抑素C对类风湿关节炎患者心血管病变的影响)

Cystatin C and Cardiovascular Disease in Rheumatoid Arthritis Patients

XUE Xiaoqian,JIANG Hong geng and XUE Wen chang   

  1. The people''s Hospital of Jieyang,The people''s Hospital of Jieyang,Outpatient Department of Chronic Disease Prevention and Control in Rongcheng
  • Received:2018-07-18 Revised:2018-11-11 Online:2018-12-25

摘要: 心血管疾病是类风湿关节炎(RA)患者最常见的死亡原因,胱抑素C是一种半胱氨酸蛋白酶抑制剂,胱抑素C水平与免疫性疾病活动和炎症显著相关,是慢性炎症强度的标志,还参与了心血管病变的进程,可作为预测RA患者心血管病变的指标。

Abstract: Cardiovascular disease is the most common cause of death in patients with rheumatoid arthritis (RA). Cystatin C is a cysteine protease inhibitor.The level of cystatin C is significantly associated with immune disease activity and inflammation, and it is a sign of chronic inflammatory intensity. It also participates in the process of cardiovascular disease. It can be used as a forecast indicator of cardiovascular disease in RA patients.