Abstract: Objective:To investigate the impact of non-verbal communication on the patients with mechanical ventilation.Methods:133 conscious cases from the intensive care unit in the department of Neurology during October 2009 to October 2010 whom were treated with mechanical ventilation were randomly divided into two groups.67 was in experimental group while 66 was in the control group.The control group was treated with conventional treatment and general care of the Department of Neurology,prescribed to regulate breathing patterns and parameters.Experimental group was treated by strengthening the non-verbal communication,such as using eyes,smiling,touching,body language,emotional exchange to understand the inner world of mechanically ventilated patients and to enhance the patients’ confidence to overcome the disease.Results: The non-verbal communication plays the role of stabling the heart rate,blood pressure,breathing and other vital indicators in mechanically ventilated patients.Conclusion: With the non-verbal communication,mechanical ventilation patient changed their cognitive to active coordinate with mechanical ventilation with a positive attitude,so that the effect of treatment was greatly enhanced and the duration of mechanical ventilation was shorten,the patient’s suffering was reduced.