Abstract: Objective:All the female clients who in the health examination were given breast palpation examination and breast color ultrasonic examination,and compared the difference in detection rates of hyperplasia of mammary glands and breast nodule between these two methods is more useful to choose better method for breast examination.Methods:Choose 789 cases female clients who were examined in our center during July to September in 2011,and compared the results between breast palpation examination and breast color ultrasonic examination.Results:The detection rate of female hyperplasia of mammary glands and breast nodule with aged 40~49 was the highest,the detection rate of breast nodule with aged 20~39 was less than 10%,the breast palpation examination has high missed diagnosis rate for breast nodule which less than 1.5cm about 72.73%.Conclusion:The breast color ultrasonic examination for female aged 40~49 should be the necessary project in health examination;people should choose more rational breast examination method in different age area.