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肺炎支原体感染肺外并发症15例临床分析

  

  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-09-25

Clinical Analysis of Extra-pulmonary Complications Caused by Mycoplasma Pneumoniae Infection

  • Received:1900-01-01 Revised:1900-01-01 Online:2012-09-25

摘要: 目的:探讨肺炎支原体(MP)感染肺外并发症发生状况及其临床特征。方法:对1992年9月到2006的10月本院儿科115例MP感染患儿。.筛选出其中有并发症患儿15例作为回顾性分析总结。结果:并发川畸病9例,占60%(9/15)均发热大于5天,其中6例眼结合膜充血、口唇皲裂、颈淋巴结肿大,全身多形性红斑、肛周潮红脱皮。2例掌跖红斑、肛周潮红脱皮。1例仅心脏B超示冠状动脉扩张。除1例转院外,其余均用"阿奇霉素"、"阿斯匹林"及"丙种球蛋白"治愈出院;并发急性传染性单核细胞增多症(简称传单)4例,占26.6%(4/15)均有发热、淋巴结肿大、咽峡炎。3例肝脾肿大。1例全身出猩红热样皮疹。均经"阿奇霉素"治愈出院;并发肺炎支原体相关性肾炎2例,占13.3%(2/15),2例均有水肿及血尿。经"阿奇霉素"抗MP,辅以对症亦全治愈出院。结论:MP感染肺外并发症多种,其中川畸病占多数60%(9/15)。各类并发症均有其相应临床特征及特定治疗方案。临床医师在治疗肺炎支原体感染的患儿时要高度警觉肺外并发症的发生,以免漏诊或误诊,错过相关的治疗时机,造成严重后果。

Abstract: Objective:To investigate the mycoplasma pneumoniae(MP) infection complication status and clinical features of extrapulmonary.Methods:115 cases of MP in hospital pediatric infections in children.from September,1996 to October,2000,of which 15 cases of complications in children as a retrospective analysis are Screened out.Results:The concurrent nine cases of Kawasaki disease,60%(9/15) having fever longer than 5 days,6 cases of eye conjunctival hyperemia,chapped lips,neck lymph nodes,systemic erythema multiforme,the perianal flushing peeling.Two cases of palmoplantar erythema,the perianal flushing peeling.only 1 cases the showing coronary artery dilatation by B ultrasound.One case transferred outside,the rest were "azithromycin","aspirin" and "gamma globulin"cured;concurrent four cases of acute infectious mononucleosis syndrome(referred to as the IM),26.6%(4/15) had fever,swollen lymph nodes,angina.Three cases had liver and spleen enlargement.One cases had systemic scarlet fever rash.ALL were cured by using "azithromycin";concurrent Mycoplasma pneumoniae associated nephritis were in two cases,accounted for 13.3%(2/15),The two cases had edema and hematuria.All were cured by using Azithromycin for anti-MP combined with symptomatic treatment.Conclusion:A variety of extrapulmonary complications are cause by MP infection.Kawasaki disease accounted for the majority of 60%(9/15).Various types of complications have the corresponding clinical features and specific treatment programs.Clinicians in the treatment of Mycoplasma pneumoniae infection in children are to be highly vigilant to extrapulmonary complications,in order to avoid being missed or misdiagnosed,missing the timing of treatment,caussing serious consequences.