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晚期食管癌放化治疗联合深部热疗的近期疗效观察

周琳,谯波,侯敏,陈波   

  1. 四川渠县人民医院肿瘤科,四川渠县人民医院肿瘤科,四川渠县人民医院肿瘤科,四川渠县人民医院肿瘤科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-01-25
  • 基金资助:
    国家医学教育发展中心课题(课题编号:2011-45-05-06),课题名称:同期放化疗联合深部热疗治疗胸段食管癌的临床观察。

Short-term Clinical Study on Deep Hyperthermia Combined with Chemoradiotherapy in the Treatment of Advanced Esophageal Cancer

Zhou Lin, Qiao Bo, Hou Min   

  1. Department of Oncology, Quxian County People's Hospital, Sichuan Province,Department of Oncology, Quxian County People's Hospital, Sichuan Province,Department of Oncology, Quxian County People's Hospital, Sichuan Province and Department of Oncology, Quxian County People's Hospital, Sichuan Province
  • Received:1900-01-01 Revised:1900-01-01 Online:2016-01-25

摘要: 目的:探讨放化疗联合深部热疗对晚期食管癌患者的近期疗效。方法:选取我院70例晚期肺癌患者,随机分为对照组和联合组。比较两组患者的近期治疗效果和不良反应情况。结果:对照组临床有效率和疾病控制率分别为62.86%和77.15%,联合组临床有效率和疾病控制率分别为85.71%和97.14%(P<0.05);联合组患者骨髓抑制、胃肠道反应和放射性食管炎发生率显著低于对照组(P<0.05)。结论:放疗联合深部热疗治疗晚期食管癌近期疗效明显,且不良反应少。

Abstract: Objective: To investigate the short-term clinical research of deep hyperthermia combined with chemoradiotherapy in the treatment of advanced esophageal cancer.Methods:A total of 70 cases of patients with advanced esophageal cancer were selected and randomly divided into control group and experiment group.The short-term clinical effect and adverse reaction between two groups were compared.Results:The effective rate and disease control rate in combination group were 62.86% and 77.15%, and those in control group were 85.71% and 97.14%(P<0.05); compared with the control group,the incidence of bone marrow suppression, gastrointestinal tract reaction and radiation esophagitis were lower in experiment group (P<0.05). Conclusion:Deep hyperthermia combined with chemoradiotherapy could improve short-term clinical effect in patients with advanced esophageal cancer, and had a positive effect in decreasing the adverse reaction.