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血清生化指标在早期先兆流产结局预测中的应用进展

夏小艳,叶枫,徐洁欢,李耀军   

  1. 长沙卫生职业学院,长沙卫生职业学院,长沙卫生职业学院,长沙卫生职业学院
  • 收稿日期:2017-02-13 修回日期:2017-09-07 出版日期:2017-11-25
  • 基金资助:
    长沙市科技局指导性科技计划项目(项目编号:K15ZD002-33;项目名称:血清β-HCG、P、SHLA-G动态变化在早期先兆流产结局预测中应用研究)

Application of Serum Biochemical Markers in Predicting the Outcome of Early Threatened Abortion

Xiao Xiao-yan,Ye Feng,Xu Jie-huan and Li Yao-jun.   

  1. Changsha Health Vocational College,Changsha Health Vocational College,Changsha Health Vocational College,Changsha Health Vocational College
  • Received:2017-02-13 Revised:2017-09-07 Online:2017-11-25

摘要: 早期先兆流产是临床常见孕早期病症之一,不仅对孕妇身心健康造成损害,也是增加社会不稳定因素之一。由于其病因尚不明确,截至目前尚无较好的治疗方法。因此,临床上如何准确预测先兆流产的结局,对该病症的治疗及后续问题有重要意义。本文通过对近几年报道的先兆流产结局预测指标的研究结果进行综述,阐述血清人绒毛膜促性腺激素、孕激素、雌激素、血清可溶性人类白细胞抗原-G、癌胚抗原125(CA125)、血清抑制素A等指标在先兆流产结局预测中的应用方法、作用及临床意义,以期给广大妇产科临床工作者及科研工作者提供一定的理论参考依据及研究思路。

Abstract: Early threatened abortion is one of the most common diseases during pregnancy. It not only damages the physical and mental health of pregnant women, but also increases the social instability. Since the etiology is not clear, so far there is no better treatment of this disease. Therefore, how to predict the outcome of threatened abortion is important for its treatment and follow-up.This paper reviews the results of predictors of threatened abortion in recent years, describes the application method, function and clinical significance of some biological indicators such as serum HCG, progesterone, estrogen, serum soluble human leukocyte antigen-G, carcinoembryonic antigen 125 and serum inhibin A, in order to provide a theoretical reference and research ideas for the vast number of obstetrics and gynecology clinical workers and scientific research workers.