Abstract: Objective:To investigate the effect and safety of myomectomy by laparoscope on subserous hysteromyoma.Methods:120 cases of patients with subserous hysteromyoma were randomly divided into laparoscope groups and control groups,the patients taken myomectomwith traditionary operation in control groups and laparoscopic in laparrosopic in laparoscope groups.Intraoperative conditions,operative effect and complication were contrasted.Results:All operations was success,time of operations was identical in two groups,bleeding amount and recuperative time was short in laparoscope groups than in control groups,incidence rate of complication was lower in laparoscope groups than in control groups,the difference was significant in statistics.Conclusion:Myomectomy by laparoscope on subserous hysteromyoma.was safe,and had good clinical effect.