Abstract: Objective:To summarize the pathogenisis and the experiences in diagnosis and treatment of duodenal stump leakage of gastric carcinoma.Methods:Retrospectively analyse total 8 duodenal stump leakage patients of post-operative gastric carcinoma ftom Jan 2004 to Jan 2009.Keeping abdominal cavity drainage patients were treated with gastrointestinal decompression,antibacterial,somatostatin,acid inhibitor,TPN,et al.If drainage was obstructed or no drainage,the second laparotomy were made decidedly to rebuilt a drainage.Results:Two cases were operated again and six cases were conservatively treated.All cases were healed.No case was died.Treating time lasted from 16 days to 34 days,mean time 26 days.Conclusion:Duodenal stump leakage could obtain a satisfying curative effect by integrative treatment.Don’t remove the drainage too early after operation and assure a gliding drainage was kept as leakage occurred was the key point.