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硫酸沙丁胺醇气雾剂吸入和茶碱控释片治疗小儿哮喘的效果对比研究

康建军1,李国华2   

  1. 1.榆林市第一医院呼吸内科2.延安职业技术学院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-06-25

  • Received:1900-01-01 Revised:1900-01-01 Online:2016-06-25

摘要: 【摘要】目的:对小儿哮喘治疗中插件控释片和硫酸沙丁胺醇气雾剂吸入的临床疗效进行探讨和分析。方法:选取2010-4~2014-12同期于我院进行哮喘治疗的小儿患儿136例,将其作为研究对象并分为观察组和对照组。对对照组患儿使用硫酸沙丁胺醇气雾剂进行吸入治疗,对观察组患儿给予硫酸沙丁胺醇气雾剂和口服茶碱控释片两种治疗手段。治疗结束后对两组患儿的治疗成效进行分析探讨。结果:对照组68例患儿中基本痊愈37例,显著进步20例,无效11例,总有效率为83.82%;不良反应方面咽部不适3例,胃部不适0例,烧心0例,发生率为4.41%。实验组68例患儿中基本痊愈19例,显著进步26例,无效23例,总有效率为66.18%;不良反应发生率方面咽部不适4例,胃部不适3例,烧心4例,发生率为14.71%。实验组较的治疗成效显著优于对照组(P<0.05),负面作用发生概率上实验组显著低于对照组(P<0.05)。结论:小儿哮喘的治疗中茶碱控释片联合硫酸沙丁胺醇气雾剂疗法的疗效十分优异,于临床上具有意义,值得进一步推广和应用。

Abstract: [Abstract]objective: plugin retard-20 tablet in treatment of infantile asthma and salbutamol sulfate aerosol inhalation of clinical efficacy were discussed and analyzed.Methods: select 2010-4-2010-12 in the same period in the hospital for treatment of 136 cases of children with infantile asthma, as research objects and were divided into observation group and control group.The control group were treated with salbutamol sulfate aerosol inhalation therapy, the observation group children give salbutamol sulfate aerosol and oral theophylline retard-20 tablet two treatments.After the treatment of two groups of children with treatment results were analyzed.Results: the control group, 68 cases of children with functional recovery of 37 cases, significant progress in 20 cases, 11 cases, the total effective rate was 83.82%;Adverse reaction in pharyngeal discomfort in 3 cases, upset stomach 0 cases, heartburn 0 cases, the incidence was 4.41%.Experimental group, 68 cases of children with functional recovery in 19 cases, remarkable progress 26 cases, 23 cases ineffective, the total effective rate was 66.18%;Incidence of adverse reactions in pharynx ministry unwell, 4 cases, 3 were upset stomach, heartburn 4 cases, the incidence was 14.71%.Experimental group a treatment effect significantly better than the control group (P < 0.05), negative probability in the experimental group was significantly lower than the control group (P < 0.05).Conclusion: the treatment of infantile asthma theophylline retard-20 tablet combination salbutamol sulfate aerosol therapy curative effect is very good, in clinical significance, is worth further promotion and application.