Abstract: Objective：To investigate the effect of enteral nutrition on NIH stroke scale (NIHSS) and nutritional status in patients with acute cerebral infarction.Methods： 90 patients with acute cerebral infarction treated in our hospital from January 2014 to January 2016 were randomly divided into the study group and the control group, and 45 cases in each group. The control group received routine nasal feeding with liquid food, and the study group was given nasal feeding with enteral nutrition.Results： After 1 day of treatment, nutritional indicators of two groups of patients had no significant difference(P>0.05).After 7 days of treatment,arm muscle circumference and serum albumin levels of patients in the study group were significantly higher than those in control group (P<0.05),and after 14 days of treatment, nutrition indicators of the study group were significantly higher than those in the control group (P<0.05).No obvious difference was observed in NIHSS score and Barthel index between two groups after 1 day of treatment (P>0.05)； after 14 days of treatment,the NIHSS score of the study group was significantly lower than that of the control group,while the Barthel index was significantly higher than the control group(P<0.05). The incidence of infection complication in the study group was 33.33%,while 62.22% in the control group, and the difference between two groups was significant (P<0.05).Conclusion： In the treatment of patients with acute cerebral infarction, the use of enteral nutrition can improve the nutritional status of patients and reduce the incidence of infection complication.