Abstract: Objective： To explore the effect of psychological intervention and Fenbid focusing on patients with dental anxiety and mental pain. Methods： 106 cases from our hospital between January 2016 and April 2017 took dental surgical treatment of dental anxiety were divided into observation group(53 cases) and control group(53 cases) and observation group patients were given the Fenbid and focused mode of psychological intervention， the control group patients were given a placebo routine intervention， compared two groups of patients 12， 48， 72h postoperatively in visual analog pain score(VAS)， self-evaluation of anxiety scale(SAS) and self rating scale for depression(SDS) to assess patients psychological status， treatment adherence and review compared two groups of patients satisfaction.Results： In the observation group， the scores of 12， 48， 72h VAS， SAS and SDS were all better than the control group， P<0.05. The treatment adherence rate of observation group was 98.11%， and the satisfaction rate was 98.11%， all higher than the control group 86.79%， 84.91%， P<0.05， and the difference was statistically significant.Conclusion： Fenbid and focused mode of psychological intervention on dental anxiety in patients with pain and psychological influence has a very positive role in patients′ postoperative pain relief， psychological state， and the treatment adherence， satisfaction is high.