国外医学领域知识库研究主题分析

国外医学领域知识库研究主题分析

陈吉,刘蕊,王盼杰,苟铃珠,杨克虎,张俊华,田金徽

兰州大学护理学院，兰州大学循证医学中心，兰州大学基础医学院,兰州大学第一临床医学院,兰州大学第一临床医学院,兰州大学第二临床医学院,兰州大学循证医学中心，兰州大学基础医学院，甘肃省智慧医学工程实验室,天津中医药大学循证医学中心,兰州大学护理学院，兰州大学循证医学中心，兰州大学基础医学院,甘肃省智慧医学工程实验室

收稿日期:2018-05-17 修回日期:2018-05-17 出版日期:2018-07-25
基金资助:
甘肃省智慧医疗工程实验室开放基金（项目编号：20170102；项目名称：人工智能在医学领域的应用）；甘肃省循证医学与临床转化重点实验室开放基金（项目编号：20170203；项目名称：循证医学方法学研究）

Analysis on the Research Topic of Foreign Knowledge Bases Studies in Medical Field

CHEN Ji,LIU Rui,WANG Panjie,GOU Lingzhu,YANG Kehu,ZHANG Junhua and TIAN Jinhui

兰州大学护理学院，兰州大学循证医学中心，兰州大学基础医学院,兰州大学第一临床医学院,兰州大学第一临床医学院,兰州大学第二临床医学院,兰州大学循证医学中心，兰州大学基础医学院，甘肃省智慧医学工程实验,天津中医药大学循证医学中心,兰州大学护理学院，兰州大学循证医学中心，兰州大学基础医学院,甘肃省智慧医学工程实验室

Received:2018-05-17 Revised:2018-05-17 Online:2018-07-25

摘要/Abstract

摘要： 目的：对国外医学领域知识库研究现状进行可视化分析，了解国外知识库研究热点，为学者今后开展医学领域知识库相关研究提供参考。方法：通过PubMed纳入国外知识库研究，采用书目共现分析系统（BICOMS-2）分析软件对发表时间、期刊、作者和主题词进行提取和整理，并生成作者和主要主题词共现矩阵，利用NetDraw绘制网络关系图，并利用gCLUTO 对主要主题词进行聚类分析。结果：国外医学领域第1篇知识库研究发表于1953年，直至2004年共计发表8篇，自2005年起文献年发表量开始上升，至2016年达到高峰。共有930种期刊刊载知识库相关文献，载文量超过50篇的共计16种期刊，其累计载文量达43.59%。共有25 961位学者参与知识库研究，发文量超过10篇的作者仅21位（0.08%），且作者间无合作关系。纳入文献共包含4 050个主题词，通过对主要主题词聚类发现3个研究主题。结论：国外医学领域知识库研究关注度呈上升趋势，但研究学者间缺乏合作，研究主题较为局限，作者间需加强合作，进一步探索研究医学领域知识库的广度与深度。

Abstract: Objective：To make visual analysis of the researches on foreign knowledge bases and obtain the research hot spots in the foreign medical field， so as to provide reference for researchers to carry out related research in the future. Methods： PubMed was searched to obtain the foreign researches on knowledge bases studies.The BICOMS-2 analysis software was used to extract the publication time， journals， authors， and medical subject headings (Mesh)， and the co-occurrence matrix of the authors and Mesh was generated. NetDraw was used to draw a network diagram and gCLUTO was used to make cluster analysis. Results： The first foreign knowledge bases research in the field of medical health was published in 1953 and a total of 8 studies have been published before 2004. From 2005， the number of studies began to increase and reached the peak in 2016. A total of 930 journals published relevant researches of knowledge bases and 16 journals have published more than 50 studies， which published 43.59% studies. 25 961 researchers took part in the researches of the knowledge bases， and only 21 (0.08%) authors published more than 10 studies， and there was no cooperation between the authors. There were 4 050 Mesh in included studies， 3 research topics were drawn through cluster analysis based on the Mesh. Conclusion： More and more researchers focus on the knowledge bases in the foreign medical field. However， there is not enough cooperation among researchers， at the same time， there is the limitation of the research topics. The authors should strength the cooperation and explore the breadth and depth of the researches in the future.

陈吉,刘蕊,王盼杰,苟铃珠,杨克虎,张俊华,田金徽. 国外医学领域知识库研究主题分析[J]. .

CHEN Ji,LIU Rui,WANG Panjie,GOU Lingzhu,YANG Kehu,ZHANG Junhua and TIAN Jinhui. Analysis on the Research Topic of Foreign Knowledge Bases Studies in Medical Field[J]. .

参考文献

[1] Trelease RB. Anatomical reasoning in the informatics age: Principles, ontologies, and agendas [J]. Anat Rec B New Anat, 2006，289B(2):72-84.
[2] 罗爱静,梁朝聪.医学知识库领域研究可视化分析[J].医学信息学杂志,2017,38(4):55-60.
[3] Brook RH, Vaiana ME. Using the Knowledge Base of Health Services Research to Redefine Health Care Systems. J Gen Intern Med,2015,30(10):1547-1556.
[4] Zulman DM, Martins SB, Liu Y, etal. Using a Clinical Knowledge Base to Assess Comorbidity Interrelatedness Among Patients with Multiple Chronic Conditions[J]. AMIA Annu Symp Proc,2015,2015:1381-1389.
[5] Cano I, Tényi á, Schueller C, etal. The COPD Knowledge Base:enabling data analysis and computational simulation in translational COPD research[J]. J Transl Med,2014,12 Suppl 2:S6.
[6] Mirzaa GM, Millen KJ, Barkovich AJ,etal. The Developmental Brain Disorders Database (DBDB): a curated neurogenetics knowledge base with clinical and research applications[J]. Am J Med Genet A. 2014,164A(6):1503-1511.
[7] Yankelevitz DF, Henschke CI. Advancing and sharing the knowledge base of CT screening for lung cancer[J]. Ann Transl Med,2016,4(8):154.
[8] Voss EA, Boyce RD, Ryan PB, etal. Accuracy of an automated knowledge base for identifying drug adverse reactions[J]. J Biomed Inform,2017,66:72-81.
[9] Lossio-Ventura JA, Hogan W, Modave F, etal.Towards an Obesity-Cancer Knowledge Base: Biomedical Entity Identification and Relation Detection[J].Proceedings (IEEE Int Conf Bioinformatics Biomed). 2016,2016:1081-1088.
[10] Ruan T, Wang M, Sun J, etal. An automatic approach for constructing a knowledge base of symptoms in Chinese[J]. J Biomed Semantics,2017,8(Suppl 1):33.
[11] Oppenheimer JJ, Marshall GD Jr. Increasing our knowledge base of asthma[J]. Ann Allergy Asthma Immunol,2017,119(6):476-479.
[12] Dumbrava EI, Meric-Bernstam F. Personalized cancer therapy-leveraging a knowledge base for clinical decision-making. Cold Spring Harb Mol Case Stud,2018,4(2). pii: a001578.
[13] Jayaratne YSN, Zwahlen RA. The evolution of dential journals from 2003 to 2112: a bibliometric analysis[J]. PLOS ONE, 2015, 10(3): e0119503.
[14] Liu DD, Liu SL, Zhang JH. Visualization analysis of research hotspots based on CiteSpace II: taking medical devices as example [J]. Med Devices (Auckl). 2014, 7: 357-361.
[15] 赵晔,张俊华,李伦,等.全球网状Meta 分析研究主题的可视化分[J].中国药物评价,2017,34(1):18-21．
[16] 康继红,陈葛舒逸,刘娟,等.国家基本药物制度研究主题的可视化分析[J].中国全科医学,2017,20(28):3471-3476.
[17] Callon M, Law J, Rip A. Mapping the dynamics of science and technology: sociology of science in the real World [M]. Wisconsin: Macmillan, 1986.
[18] 陈军,谢卫红,陈扬森,等.国内外大数据可视化学术论文比较研究——基于文献计量与SNA方法[J].科技管理研究,2017,37(8):44-53.
[17] Callon M, Law J, Rip A. Mapping the dynamics of science and technology: sociology of science in the real World [M]. Wisconsin: Macmillan, 1986.
[18] 陈军,谢卫红,陈扬森,等.国内外大数据可视化学术论文比较研究——基于文献计量与SNA方法[J].科技管理研究,2017,37(8):44-53.

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