Abstract: Objective：To explore the efficacy of oxybuprocaine hydrochloride gel combined with tetracaine topical anesthesia on removal of pharyngolaryneal foreign body under electronic laryngoscopy. Methods：Ninety emergency patients undergoing removal of pharyngolaryneal foreign body under electronic laryngoscopy were randomly divided into 3 groups(30 cases in each group).Patients in group A received oxybuprocaine hydrochloride gel.Patients in group B received tetracaine topical anesthesia and patients in group C received both oxybuprocainehydrochloride gel and tetracaine.The efficacy of anesthesia and unfitness visual analogue scales(VAS) were recorded.Results：The marked improvement rate of anesthetic efficacy in group C(83.3%) was higher than those in group A(66.7%）and group B(60%)（P<0.05）.But there was no statistically significant difference in the total effective rate among 3 groups(P>0.05). The unfitness VAS in group C was lower than group A and group B（P<0.05）.Conclusion：Oxybuprocaine hydrochloride gel combined with tetracaineon topical anesthesia in pharyngolaryneal foreign body removal under electronic laryngoscopy is effective and safe， and with high patient acceptance.