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中药药枕对肝郁化火型失眠影响的临床研究

郑舒月,王媛媛,杨菲,彭浩轩,严玉倩,陈明   

  1. 北京中医药大学中医学院,北京中医药大学中医学院,北京中医药大学中医学院,北京中医药大学中医学院,北京中医药大学中医学院,北京中医药大学中医学院
  • 收稿日期:2018-08-08 修回日期:2018-08-30 出版日期:2018-09-25
  • 基金资助:
    北京市大学生科学研究与创业行动计划专项2016年度项目(项目编号:BJGJ1618;项目名称:中药药枕改善失眠症状的研究);2018年西藏自治区自然科学基金项目(项目编号:XZ 2018 ZR G-127;项目名称:藏药如意珍宝丸干预PD小鼠脑线粒体动力学机制研究)

Clinical Research on Traditional Chinese Medicine Pillow in Treating Liver-fire Type Insomnia

ZHENG Shuyue,WANG Yuanyuan,YANG Fei,PENG Haoxuan,YAN Yuqian and CHEN Ming   

  1. School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing,School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing,School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing,School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing,School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing,School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing
  • Received:2018-08-08 Revised:2018-08-30 Online:2018-09-25

摘要: 目的:探究中药药枕对肝郁化火型失眠的影响。方法:选取2016年5月至2017年2月符合纳入标准的60例肝郁化火型失眠患者作为研究对象,按照随机数字表法将其分为观察组和对照组两组,每组各30例。观察组采用丹栀逍遥散加减为主方的药枕治疗,对照组给予荞麦皮芯作为安慰剂进行枕头治疗。依据匹兹堡睡眠质量指数(PSQI)量表比较两组患者睡眠质量,并参照国家中医药管理局《中医病证诊断疗效标准》来评估疗效,运用SPSS统计软件进行数据分析。结果:治疗3个月后,观察组患者的PSQI评分下降,治疗前后差异有统计学意义(P<0.01),与对照组相比较,差异有统计学意义(P<0.05);且在观察组PSQI各项积分中,睡眠质量、睡眠时间、睡眠障碍和日间功能障碍这4项积分有所下降,差异有统计学意义(P<0.05),治疗的总有效率为76.67%。治疗6个月后的总有效率为100%。结论:中药药枕能够改善肝郁化火型失眠的临床症状,提高患者的睡眠质量,促使睡眠结构合理化,且无明显不良反应。其中中青年患者缓解速度较快,而老年患者则需要较长的治疗时间。

Abstract: Objective:To investigate the effect of traditional Chinese medicine(TCM) pillow in treating liver-fire type insomnia. Methods: 60 patients suffering from liver-fire type insomnia who met the inclusion criteria from May 2016 to February 2017 were selected as subjects, and allocated them randomly into two groups,the observation group (n=30) and the control group(n=30). The observation group were treated with the pillow having TCM,and the control group were treated with the pillow having buckwheat husk.Evaluate whether TCM pillow can treat liver-fire type insomnia via pittsburgh sleep quality index (PSQI),standard of diagnosis and curative effect. SPSS statistical software was used to assess and analysis for data.Results:After treating for 3 months,PSQI scores of patients in the observation group descended and had statistically differences(P<0.01).Compared with the control group, PSQI scores also had statistically differences(P<0.05).And the indexes of the sleeping quality,sleeping time,the disorders of sleeping and activities in the daytime of the observation group descended, which were statistically significant compared with the patients of the control group(P<0.05).The total effective rate was 76.67% after 3 months, and 100% after 6 months. Conclusion:TCM pillow can improve the clinical symptoms of the liver-fire type insomnia and the sleeping quality, rationalize the structure of the sleep without evident side effects.The young patients have a quicker response to the TCM pillow than the old patients.