Abstract: Undiagnosed early-stage chronic obstructive pulmonary disease (COPD) is likely to become more severe with time. Initiating treatment early in the course of COPD is likely to slow disease progression and improve health-related quality of life (HRQoL). Through literature review， this paper summarizes the early intervention measures for COPD include smoking cessation， bronchodilators and lung rehabilitation. Smoking cessation can reduce lung function decline at early or mild stage COPD. Long-acting bronchodilators， include LAMA， LABA/LAMA and LABA/ICS can slow the decline of lung function， as well as reduce exacerbation and mortality rates and improve HRQoL in patients with mild-to-moderate COPD. Pulmonary rehabilitation might improve symptoms and exercise tolerance， and reduces the risk of acute exacerbations of COPD. To give standardized and systematic “early intervention” to patients with COPD and to improve the popularizing rate of diagnosis and treatment of early COPD is the breakthrough point of prevention and control of COPD.