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中国医药导刊 ›› 2019, Vol. 21 ›› Issue (12): 757-761.

• 管理与实践 • 上一篇    下一篇

《中华人民共和国药典临床用药须知(2015年版)》中含半夏炮制品成方制剂收载情况分析

闫红敏,女,副主任中药师,研究方向:中药制剂和中医药膳学研究。E-mail: 13703717538@163.com   

  1. 1. 河南省直第三人民医院
         2. 河南中医药大学第二临床医学院
         3. 河南中医药大学第一附属医院药学部
  • 收稿日期:2020-02-10 修回日期:2019-12-17 出版日期:2019-12-31 发布日期:2019-12-31

Analysis of the Inclusion of Set Prescription Preparation Containing Pinellia Ternata and Its Processed Products in 2015 Edition of Chinese Pharmacopeia Guidelines for Clinical Drug Use

  1. 1. The Third People's Hospital of Henan Province
         2. The Second Clinical Medical College, Henan University of Traditional Chinese Medicine
         3. Department of Pharmacy, The First Affiliated Hospital of Henan University of TCM
  • Received:2020-02-10 Revised:2019-12-17 Online:2019-12-31 Published:2019-12-31

摘要: 目的:为含半夏及其炮制品成方制剂合理应用提供参考。方法:对2015年版《中华人民共和国药典临床用药须知》(以下简称《临床用药须知》)(中药成方制剂卷)一书含半夏及其炮制品成方制剂的收载情况进行汇总、分析。 结果:《临床用药须知》中共收载含半夏及其炮制品成方制剂98种,其中内科、妇科、儿科、咽喉科、骨伤科类制剂分别有81、2、11、1、3种;以半夏为君、臣、佐药的成方制剂分别有8、42、48种;按剂型分类,固体制剂、液体制剂分别有84、14种;含生半夏、制半夏的成方制剂分别有13、30种,含清半夏、姜半夏、法半夏、半夏曲的分别有9、12、33、1种。结论:通过归纳、分析,发现该书中半夏及其炮制品的临床应用、标示等方面与《中国药典》存在不统一之处,应加强对有毒中药的炮制规范、减毒机理研究,以期为临床合理用药提供更加准确的理论指导。

Abstract: Objective: To provide reference for the rational use of set prescription preparation containing Pinellia ternata and its processed products. Methods: The inclusion of set prescription preparations containing Pinellia ternata and its processed products in the 2015 edition of Chinese Pharmacogeia Guidelines for Clinical Drug Use(hereinafter referred to as Guideline For Clinical Drug Use) (TCM prescription preparation volume) were summarized and analyzed. Results: In the 2015 edition of Guideline For Clinical Drug Use, totally 98 kinds of prescription preparations containing Pinellia ternata and its processed products are included, among which 81, 2, 11, 1 and 3 kinds are for internal medicine, gynecology, pediatrics, pharyngology and orthopedics respectively. There are 8, 42 and 48 kinds of prescription preparations using Pinellia ternate as monarch medicine, minister medicine and adjuvant medicine respectively. Classified by dosage form, there are 84 kinds of solid preparations and 14 kinds of liquid preparation. Prescription preparations containing raw Pinellia ternata are 13 kinds, prescription preparations containing processed Pinellia ternate are 30 kinds, and prescription preparations containing alum processed Pinellia, ginger processed Pinellia, processed Pinellia tuber, and fermented Pinellia, are 9, 12, 33, and 1 kinds respectively. Conclusion: After summarizing and analyzing the efficacy and application of Pinellia ternata and its processed products, it was found that applications and labelings of Pinellia ternata and its processed products were not uniform. To provide a more accurate theoretical guidance for rational drug use, research on processing standards for toxic drugs and attenuated mechanism should be strengthened.

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