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中国医药导刊 ›› 2020, Vol. 22 ›› Issue (5): 305-3090.

• 临床医学 • 上一篇    下一篇

儿童孤独症谱系障碍中医临床路径应用研究

赵宁侠, 杜晓刚*, 宋虎杰, 闫炳苍, 焦文涛, 樊亚妮, 张倩, 郭凯, 高峰, 张宁勃, 刘银侠   

  1. 西安中医脑病医院脑病十科, 陕西 西安710032
  • 收稿日期:2020-03-17 修回日期:2020-05-23 出版日期:2020-05-31 发布日期:2020-06-19
  • 基金资助:
    2017年陕西省中医药管理局科研项目(项目编号:No.LCPT130;项目名称:孤独症谱系障碍中医临床路径应用研究);陕西省重点研发计划项目(项目编号:No.2017ZDXM-SF-006;项目名称:儿童孤独症中医诊疗规范研究)

Application of Traditional Chinese Medicine Clinical Pathway for Children with Autism Spectrum Disorder

  1. Xi′an Encephalopathy Hospital of Traditional Chinese Medicine, Shaanxi Xi ′an 710032,China
  • Received:2020-03-17 Revised:2020-05-23 Online:2020-05-31 Published:2020-06-19

摘要: 目的:观察儿童孤独症谱系障碍中医临床路径应用的效果。方法:纳入2017年10月至2019年10月我院确诊为孤独症谱系障碍的住院和门诊患儿100例,采取随机双盲方法分为观察组和对照组各50例。对照组不纳入路径,给予选择性康复训练,观察组纳入孤独症谱系障碍中医临床路径治疗。治疗前后采取《孤独症儿童心理教育评核(第三版)》(C-PEP-3)、儿童孤独症评定量表(CARS)、孤独症行为量表(ABC)评分,一疗程后根据疗效评价标准观察两组患儿的疗效及路径可行性。结果:两组患儿治疗前C-PEP-3、ABC、CARS评分,差异无统计学意义(P>0.05)。两组患儿治疗后C-PEP-3评分均较治疗前升高(P<0.01),且治疗组较对照组升高更为显著(P<0.01)。两组患儿治疗后ABC评分均较治疗前降低(P<0.01),且治疗组较对照组降低更为显著(P<0.01)。两组患儿治疗后CARS评分均较治疗前降低(P<0.01),治疗组较对照组降低更为显著(P<0.05)。观察组患儿总有效率88%,高于对照组总有效率54 %(P<0.05)。结论:纳入孤独症谱系障碍中医临床路径治疗,效果显著提高。

关键词: font-size:medium, ">儿童孤独症谱系障碍;中医临床路径;疗效

Abstract: Objective: To observe the effect of traditional Chinese medicine clinical pathway in children autism spectrum disorder. Methods: A total of 100 inpatients and outpatients with "autism spectrum disorder" diagnosed in our hospital from October 2017 to October 2019 were divided into the control group and the observation group,each 50 cases. The control group was not included in the clinical pathway, gave selective rehabilitation training. The observation group was included in autism spectrum disorder clinical pathway of traditional Chinese medicine treatment. Before and after treatment,the third edition of the autistic children′s psychological education assessment (C-PEP-3), children autism rating scale (CARS) score and autism behavior chectlist(ABC) score were used. After a period of treatment, according to the curative effect evaluation standard to observe the curative effect of the two groups and the feasibility of the pathway. Results: The scores of C-PEP-3, ABC and CARS of the two groups before the treatment were compared, and the difference was not statistically significant (P>0.05).The C-PEP-3 scores of the two groups after treatment were significantly higher than those before treatment(P<0.01), and the increase in the treatment group was more than that in the control group(P<0.01).The ABC scores of the two groups after treatment were significantly lower than those before treatment(P<0.01), and the reduction was more significant in the treatment group than that in the control group (P<0.01).The CARS scores of the two groups after treatment were significantly lower than those before treatment(P<0.01).The reduction in the treatment group was more significant than that in the control group(P<0.05).The total effective rate was 88% in the observation group which was better than 54% in the control group(P<0.05).Conclusion: Adopting clinical pathway of traditional Chinese medicine in the treatment of autism spectrum disorder can improve curative effect.

Key words: font-size:medium, ">Children autism spectrum disorder; Clinical pathway of traditional Chinese medicine; Curative effect

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