癌症化疗期间合并急性胰腺炎的中西医结合防治体会

摘要/Abstract

摘要： 目的:探讨癌症化疗期间合并急性胰腺炎（AP）的中西医结合预防及治疗措施。方法:选取2016年3月至2021年5月我院收治的癌症化疗期间合并AP的36例患者作为研究对象,所有患者给予胰腺炎胰腺疾病三结合方案治疗。所有痊愈好转的34例癌症合并AP患者，再入院时均施以强化中医药为主的六位一体疗法。记录患者不良反应及治疗结局。结果:化疗IV级消化道反应23例，Ⅲ级消化道反应13例；轻症AP共25例，中度重症AP共8例，重症AP共3例（死亡2例）。经治疗，34例痊愈好转，并经后续六位一体疗法未再出现Ⅲ、Ⅳ级消化道反应。结论:癌症化疗过程中，要严密监控化疗期间的不良反应及其并发症，高度重视癌症化疗期间合并AP的中西医结合防治。

关键词: font-size:medium, ">癌症；急性胰腺炎；六位一体诊疗模式；不良反应；中西医结合

Abstract: Objective: To explore the prevention and treatment measures of acute pancreatitis（AP）during cancer chemotherapy. Methods: 36 patients with AP during cancer chemotherapy admitted in our hospital from March 2016 to May 2021 were selected as the research objects. All patients were treated with the “three-binding” treatment program for pancreatic disease in pancreatitis. All 34 patients with cancer and AP were given six-in-one personalized treatment, and strengthen traditional Chinese medicine during treatment when they were re-admitted to the hospital.And the patient′s adverse reactions and treatment outcomes were recorded. Results: There were 23 cases of grade IV gastrointestinal reaction and 13 cases of grade Ⅲ gastrointestinal reaction during cancer chemotherapy.There were 25 cases with mild AP(MAP),8 cases of moderate severe AP(MSAP),3 cases of severe AP(SAP), and 2 deaths in this SAP group. Conclusion: During cancer chemotherapy, it is necessary to monitor the adverse reactions and complications，pay more attention to the integrated traditional Chinese and western medicine prevention and treatment of AP response during cancer chemotherapy.

Key words: Cancer;Acute pancreatitis, Six-in-one diagnosis and treatment mode;Adverse reactions;Integrated traditional Chinese and western medicine

中图分类号:

朱建平, 侯小兵, 牟东成, 李永猛, 华玲莉, 肖雪, 赵帅, 徐铭康, 刘芳, 李司航. 癌症化疗期间合并急性胰腺炎的中西医结合防治体会[J]. 中国医药导刊, 2021, 23(11): 819-822.

ZHU Jianping, HOU Xiaobing, MOU Dongcheng, LI Yongmeng, HUA Lingli, XIAO Xue, ZHAO Shuai, XU Mingkang, LIU Fang, LI Sihang. Experience of Integrated Traditional Chinese and Western Medicine in Prevention and Treatment of Acute Pancreatitis during Cancer Chemotherapy[J]. CHINESE JOURNAL OF MEDICINAL GUIDE, 2021, 23(11): 819-822.

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