关键词: font-size:medium, ">通塞脉胶囊；介入手术；糖尿病足；临床研究

Abstract: Objective： To observe the clinical efficacy of Tongsaimai capsules combined with interventional surgery in the treatment of diabetic foot. Methods： 80 patients with diabetic foot were randomly divided into the control group and the observation group， 40 cases in each group. The control group was given interventional surgery， and the observation group was given Tongsaimai capsules after interventional surgery. Serum inflammatory factors [tumor necrosis factor-α(TNF-α)， interleukin-6 (IL-6)]， blood glucose indicators [fasting blood glucose (FPG)， 2 h postprandial blood glucose (2hPG)]， and hemodynamics of dorsal foot artery (arterial diameter， arterial blood flow velocity) were observed in the two groups. Results： The total effective rate was 97.5% (39/40) in the observation group， which was higher than 82.5% (33/40) in the control group (P<0.05). Compared with the control group 3 months after surgery， TNF-α， IL-6， FPG and 2hPG in the observation group reduced more obviously than those in the control group (P<0.05)， and arterial diameter and arterial blood flow velocity increased more obviously than those in the control group (P<0.05). There was no statistical difference in the incidence of complications between the two groups (P>0.05). Conclusion： Tongsaimai capsules combined with interventional surgery can effectively improve the level of inflammatory factors， blood glucose indicators， and hemodynamics of dorsal foot artery of diabetic foot patients.

Key words: font-size:medium, ">Tongsaimai capsules； Interventional surgery； Diabetic foot； Clinical research