关键词: 育龄妇女, 生殖毒性药物, 合理用药, 科普宣教

Abstract: Objective： To investigate the usage of reproductive toxic drugs in fertile woman， ensure the safety of drug use during pregnancy， and reduce the birth defects caused by drugs. Methods： The fertile woman in Hunan province were selected as the research objects， and the questionnaire was made by "questionnaire star". The questionnaire was analyzed from the basic information of women of childbearing age， folic acid supplement， knowledge of safe drug use， use of reproductive toxic drugs and other aspects. Results： 637 valid questionnaires were collected， 55.42% of them had bachelor degree or higher education. 51.8% of fertile woman were pregnant in a planned way. 65.93% of fertile woman could supplement folic acid before pregnancy. 94.35% of fertile woman had high risk awareness of drug-induced teratogenesis， and 5.34% of fertile woman used reproductive toxic drugs during pregnancy. Conclusion： Science education on the rational use of reproductive toxic drugs for women of childbearing age should be strengthen， to guide women of childbearing age to conceive in a planned way， and supplement folic acid regularly. It is suggested that relevant policies and specific management measures should be operated， and the supervision of reproductive toxic drugs should be strengthened to reduce the birth defects.

Key words: Fertile woman； , Reproductive toxic drugs； , Rational use of drugs； , Popularization science education