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中国医药导刊 ›› 2023, Vol. 25 ›› Issue (4): 416-419.

• 中医中药 • 上一篇    下一篇

经典名方开心散及其类方中医文献研究概述

    殷俊梅1, 王偲2, 丁侃3, 高雅3*, 杨忠奇1*   

  1. 1.广州中医药大学第一附属医院, 广东 广州 510405;
    2.华润三九医药股份有限公司, 广东 深圳 518000;
    3.中国中医科学院中国医史文献研究所, 北京 100700
  • 收稿日期:2023-06-05 修回日期:2023-05-08 出版日期:2023-04-28 发布日期:2023-04-28
  • 基金资助:
    国家社会科学基金(项目编号:22CMZ042;项目名称:元代汉蒙民族饮食养生文化交互影响史证研究);中国中医科学院科技创新工程项目(项目编号:CI2021A00303;项目名称:基于中医药传统知识保护需求的古方数据库建设)

Overview of Traditional Chinese Medicine Literature Researches on Classical#br#      Famous Formula Kaixin Powder and Its Categorized Formula

  1. 1.The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangdong Guangzhou 510405, China;
    2.China Resources Sanjiu Medical & Pharmaceutical Co., Ltd, Guangdong Shenzhen 518000, China;
    3.Institute of Chinese Medical History and Literature, Chinese Academy of Traditional Chinese Medicine, Beijing 100700, China
  • Received:2023-06-05 Revised:2023-05-08 Online:2023-04-28 Published:2023-04-28

摘要: 《备急千金要方》开心散为古代经典名方之一,是中医临证治疗“好忘”的常用方。后世医家应用过程中,衍化出了许多类方,其功能主治与《备急千金要方》开心散既有“守正”又有“创新”,因此考证本方与类方的功能主治十分必要。开心散“主好忘”,药物剂量经度量衡换算,远志、人参、茯苓及菖蒲剂量依次为13.8、13.8、27.6、13.8 g,比例为1∶1∶2∶1。这与《古代经典名方关键信息表(25首方剂)》所列一致,后世医家扩大了开心散的治疗范围,可以治疗因心气不足,胆气实热导致的心悸怔忡及遗精等。本研究经文献梳理及专家认定,挖掘定志丸、令人不忘方、远志散、小定志丸、远志丸、加味定志丸、菖蒲益智丸等7个类方,发现通过药味变化,加茯神,更补心气,令人不忘;加黄连,可清心除烦,交通心神;加朱砂、龙齿,清心定悸,镇惊安神;加郁金、琥珀,除痰凉血,安神定悸;加桂心、附子,可通阳散寒,定悸宁神。此外,本研究通过两则验案说明该方的应用范围与法度。开心散的文献挖掘整理模式可为进一步开展古代经典名方系列研究提供范例。

关键词: font-size:medium, ">经典名方;开心散;类方;中医文献

Abstract: Kaixin powder in “Beiji Qianjin Yao Fang”, as one of the classical famous formulas of Chinese medicine, is a commonly used formula in traditional Chinese medicine for treating “ forgettery ”.In the process of later application, a number of categorized formulas have been derived. Compared with kaixin powder in “Beiji Qianjin Yao Fang”, their functions and indications have both “integrity” and “innovation”, so it is necessary to research the functions and indications of kaixin powder and its categorized formulas. The dosage of polygala tenuifolia, ginseng, poria cocos and calamus in kaixin powde were 13.8, 13.8, 27.6,13.8 g, and their ratio was 1∶1∶2∶1, which was consistent with the “Key Information Table of Ancient Classical Famous Formulas of Chinese Medicine”. Later doctors expanded the treatment range of kaixin powder, such as to treat palpitation. In this study, after literature review and expert identification, 7 kaixin powder categorized formulas were analyzed, which found that adding fu shen can tonifying heart-Qi, addiing coptis can clear the heart heat, adding cinnabar, dens draconis can clear heart and settle palpitation, adding radix curcumae and chrysophoron can calm down palpitation; adding cinnamon and aconite can calm the mind. In addition, this study illustrates the application range and method of this formula through two cases. The document mining model of kaixin powder can provide an example for further research on ancient classical famous formulas.

Key words: font-size:medium, ">Classical famous formula of Chinese medicine; Kaixin powder; Categorized formula; Traditional Chinese medicine literature

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