• 中国核心期刊(遴选)数据库收录期刊
  • 中文科技期刊数据库收录期刊
  • 中国期刊全文数据库收录期刊
  • 中国学术期刊综合评价数据库统计源期刊等

快速检索引用检索图表检索高级检索

中国医药导刊 ›› 2024, Vol. 26 ›› Issue (1): 44-47.

• 精准医疗良好实践案例:创新实践 • 上一篇    下一篇

精准医疗临床研究的关键挑战与优化建议

杜静婷1, 冷烨1, 祁婉婷2, 韩洞明34, 王丽丽3, 黄慧瑶1*, 王闻雅2*, 李宁1*   

  1. 1.国家癌症中心,中国医学科学院肿瘤医院,北京 100021;
    2.清华大学附属北京清华长庚医院,北京 102218;
    3.深圳华大生命科学研究院,广东 深圳 518083;
    4.中国科学院大学生命科学学院,北京 100049
  • 收稿日期:2024-01-04 出版日期:2024-01-28 发布日期:2024-01-28
  • 基金资助:

    国家重点研发计划资助项目,科技部重点研发计划“政府间国际科技创新合作”重点专项[项目编号:2021YFE0192400;项目名称:中国-欧盟国际精准医疗领域合作支持计划(IC2PerMed)]

Key Challenges and Optimization Recommendations of Clinical Research for Personalised Medicine

  1. 1.National Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences Beijing 100021,China
    2.Beijing Tsinghua Changgung HospitalBeijing 102218,China
    3.BGI ResearchGuangdong Shenzhen 518083,China
    4.College of Life Sciences University of Chinese Academy of Sciences Beijing 100049,China
  • Received:2024-01-04 Online:2024-01-28 Published:2024-01-28

摘要:

近年来,随着现代生物技术的成熟,在国际社会共同推动下,致力于为患者提供个性化医疗服务的精准医疗及其相关临床研究取得了显著进展。为促进精准医疗研究及其发展环境的优化,欧盟委员会设立了国际精准医疗联盟(ICPerMed),以专项研究的形式支持精准医疗健康发展。ICPerMed2020年启动PERMIT专项,该专项致力于推动精准医疗临床研究的发展。本研究围绕PERMIT专项的概况、研究目标、工作内容及其针对精准医疗临床研究发展的相关工作建议等几个方面进行系统介绍;同时结合我国精准医疗临床研究的进展与挑战,提出促进精准医疗临床研究健康高效发展的若干关键工作方向,包括政策制定、监管框架和资金投入等,以供相关工作参考。


关键词: 精准医疗, 临床研究, ICPerMed, PERMIT项目, 肿瘤精准治疗

Abstract:

 In recent years with the maturity of modern biological technology and the joint promotion of the international community personalised medicine and its clinical research which is dedicated to providing personalized medical services to patientshave made significant progress. In order to promote personalised medicine research and optimize its ecological environment the European Commission established the International Consortium of Personalised Medicine ICPerMed to support the healthy development of personalised medicine in the form of project research. ICPerMed set the PERMIT project in 2020 which is dedicated to promoting the development of clinical research for personalised medicine.This study systematically introduces the overview research goals work content of PERMIT and its related work suggestions for the development of clinical research for personalised medicine. At the same time combined with the progress and challenges of clinical research for personalised medicine in China this study proposes several key work directions to promote healthy and efficient development of clinical research for personalised medicine including policy formulation regulatory framework and financial investment so as to provide reference for related work.


Key words: Personalised medicine , Clinical research , ICPerMed , PERMIT project , Precision oncology

中图分类号: