关键词: 呼吸系统, 潜在不适当用药, Beers标准, 影响因素, 营养风险

Abstract:

Objective： To analyze the influential factors for potentially inappropriate medication（PIM）of elderly inpatients in respiratory department， in order to provide references for clinical drug application．Methods： The clinical data of 323 elderly inpatients in the respiratory department of our hospital were collected . According to 2023 American Geriatrics Society Beers Criteria（hereinafter referred to as the “2023 version of Beers criteria”）， the PIM status of elderly inpatients in the respiratory department was analyzed. Multivariate Logistic regression analysis was used to identify influential factors for PIM.Results： 127 patients （39.32%） had PIM， of which 57（44.88%） had PIM related to drugs， 19（14.96%） had PIM related to diseases or symptoms， 40（31.50%） had PIM that should be used with caution，19（14.96%）had PIM with drug-drug interaction that should be avoided，and 10（7.87%） had PIM based on renal function. The drug involved mainly included benzodiazepines，aspirin， proton pump inhibitors，NSAIDs and diuretic. Multivariate Logistic regression analysis showed that the number of diseases， types of medication and nutritional risk were risk factors of PIM.The treating physician held a senior professional title was protective factor.Conclusion： The risk of PIM in elderly hospitalized patients in respiratory departement increases with the increase of disease number， medication types and malnutrition. Clinicians and pharmacists should pay attention to PIM related risk factors，and promote rational drug use.

Key words: Respiratory system； , Potentially inappropriate medication； , Beers criteria； , Influence factors； , Nutritional risk