Abstract: Objective：To analyze the current research status of research topic and the researcher cooperation ability of expert systems in China，so as to provide reference for future research of expert systems in medical field. Methods：We systematically searched major Chinese databases（CBM，CNKI，Wanfang）， and included all available studies of expert systems in Chinese papers， and extracted the related information (year， province， researcher and institutions) and produced co-matrix by BICOMS-2 software， the figure of network was pro-duced by NetDraw，cluster analysis was performed by gCLUTO. Results：A total of 629 studies on expert systems were included. The number of studies in recent years has been the volatility or even decline. The researchers and institutions come from 28 provinces(citys)in China. There were six teams between the author cooperation，and there were three main research topics. Conclusion：There are many researchers and institutions involved in expert systems research in China，but lack of cooperation or cooperation is not close enough，and there was obvious geographical imbalance，and the research topic is narrow.Therefore，it is suggested that the authors， institutions and provinces should further strengthen cooperation and expand the research subject in the future.