关键词: 瑞士, 个性化健康网络, 个性化医疗, 患者数据共享, 全生命周期纵向数据, 多重慢病

Abstract:

Switzerland has an excellent reputation in the field of personalized medicine. Swiss Personalized Health Network （SPHN） is known for its high efficiency， privacy， high technology and excellent quality of service， and is often regarded as a model for global healthcare services. Focusing on the important role of SPHN in supporting personalized medicine in Switzerland， this study investigates the strategic trends， policy and legal support， organizational structure and operation of personalized medicine in Switzerland， and points out three key factors for the development of Swiss personalized medicine： ①efficient operation of the SPHN organization；②special protection mechanisms for patient data sharing； and ③highly interoperable data sharing infrastructure. Based on top-down and bottom-up financial support， SPHN has achieved a balance of multiple stakeholders， including university hospitals， universities， technology platforms， patients and other data-generating institutions， and constructed a series of major data-sharing infrastructures （e.g. BioMedIT） under the operation of the Data Coordination Center （DCC）， in order to practically support the R&D program and accommodate the further application of machine learning， artificial intelligence， and multi-omics analysis techniques. In the future， Switzerland plans to gradually strengthen personalized medical data sharing in its "top-level design" in order to improve the lifelong longitudinal data， and to strengthen the support of data sharing for the diagnosis of multimorbidity， which to a certain extent represents the latest trend in the development of personalized medicine in Europe.

Key words: Switzerland； , SPHN； , Personalized medicine； , Patient data sharing； , Lifelong longitudinal data； , Multimorbidity