关键词: 医学教育, 基础医学, 学科竞赛, 改革创新

Abstract:

Objective： Through in-depth analysis of the award-winning works of the "Basic Clinical" track in the 9th National Forum for Undergraduate on Innovation Research & Experimental Design Competition， to identify the research hotspots and trends in this field， point out the research frontiers in the discipline for future participating teams， and provide empirical data on the education and teaching reform and competition development dynamics for medical colleges and universities.Methods： Excel 2023， VOSviewer 1.6.18 and other softwares were used to analyze the award-winning works published on the official website of the 9th National Forum for Undergraduate on Innovation Research & Experimental Design Competition. The regional， provincial and university distribution of the award-winning works of "Basic Clinical" track were presented in the form of visual map， and the theme keywords of the award-winning works were analyzed by clustering.Results： A total of 611 works were awarded in the last round of this competition， which was divided into the categories of innovative research and experimental design， covering five disciplines including basic clinical， preventive medicine， forensic medicine， traditional Chinese medicine and stomatology， with an award percentage of 14.32%.Among them， 335 works won the awards in the basic clinical track， including 67 gold awards， 100 silver awards， and 168 bronze awards. The 335 award-winning works in basic clinical disciplines are mainly concentrated in East China and South China， and "double first-class" universities and "old brand" medical colleges are the main force to win the award. The award-winning works mainly focus on nine aspects： the regulatory effects of JAK-STAT， PI3K-Akt signaling pathway and osteopontin （OPN） on diabetes and nonalcoholic fatty liver disease； the effect of macrophage polarization and PD-L1 on breast cancer； the mechanism of ferroptosis in cerebral ischemia-reperfusion injury and liver injury； the role of glial cells in sepsis associated encephalopathy； inhibitory effect of hydrogen sulfide on pyro-ptosis of vascular endothelial cells and macrophages； ameliorating effect of mesenchymal stem cell-derived exosomes on osteoporosis and the regulatory role of endoplasmic reticulum stress on liver cancer and hypertension； the regulatory role of hydrogel， Nrf2 pathway and copper death in brain injury； the inhibitory effect of T cells on asthma and the efficacy of drug combination on pain， and immunotherapy of tumors such as lung cancer and melanoma.Conclusion： As the most influential college student innovation design competition in the field of basic medical education in China， the level of entries in National Forum for Undergraduate on Innovation Research & Experimental Design Competition is significantly different among different regions and universities， which highlights the urgent need for dynamic empirical data on the development of the competition. Universities should build competition data collection and analysis systems based on big data and provide professional competition guidance， carry out inter-regional cooperation and exchanges， explore the construction of basic medical virtual laboratories， so as to achieve the co-construction and sharing of high-quality education resources， and establish a long-term tracking and evaluation mechanism to support the continuous improvement of this competition and to promote the high-quality development of medical education.

Key words:  , Medical education； , Basic medicine； , Academic competition； , Reform and innovation