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中国医药导刊 ›› 2025, Vol. 27 ›› Issue (11): 1215-1215-1223.doi: magtech.2025.01.06-00002

• 医药信息学 • 上一篇    下一篇

基于CNKI的代谢相关脂肪性肝病中医药研究知识图谱分析

卢存存1, 王海博2, 张强3, 王志飞4*   

  1. 1.甘肃中医药大学 中西医结合研究所,甘肃 兰州 730101;

    2.甘肃中医药大学附属医院,甘肃 兰州 730000;

    3.河南中医药大学第一附属医院,河南 郑州 450000;

    4.中国中医科学院 中医临床基础医学研究所,北京 100700
  • 收稿日期:2025-01-06 修回日期:2025-01-21 接受日期:2025-03-14 出版日期:2025-11-28 发布日期:2025-12-24
  • 基金资助:
    中国中医科学院科技创新工程项目(CI2021A00702)

Knowledge Mapping of Traditional Chinese Medicine for Metabolic Dysfunction-associated Steatotic Liver Disease based on CNKI

LU Cuncun1, WANG Haibo2, ZHANG Qiang3, WANG Zhifei4*   

  1. 1.Institute of Traditional Chinese and Western Medicine Gansu University of Chinese Medicine Gansu Lanzhou 730101, China
    2.Affiliated Hospital of Gansu University of Chinese Medicine Gansu Lanzhou 730000, China
    3.The First Affiliated Hospital of Henan University of CM Henan Zhengzhou 450000, China
    4.Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences Beijing 100700, China
  • Received:2025-01-06 Revised:2025-01-21 Accepted:2025-03-14 Online:2025-11-28 Published:2025-12-24

摘要:

目的:基于文献计量学对代谢相关脂肪性肝病中医药诊疗研究现状与热点进行定量分析。方法:计算机检索中国知网收集相关研究文献,检索时限为建库至202461日。两位研究者独立筛选文献并交叉核对结果,以确定纳入分析的文献。利用VOSviewer对年发文量、省市地区、作者、机构、期刊和关键词进行统计分析,并绘制相应的知识图谱。结果:纳入发表于19982024年的3529篇文献,年发文量总体上呈上升态势,文献来自全国30个省级行政区域,且以上海(351篇)和北京(316篇)的发文量最多。在1811个机构中,尤以中医药类大学及其附属医院的发文量最多,其中上海中医药大学附属曙光医院(128篇)发文量位列第一;在7842名作者中,赵文霞教授(69篇)和李军祥教授(60篇)的发文量最多,但该领域不同机构或者学者间的合作关系尚不密切。在385本期刊中,《中西医结合肝病杂志》刊文量最多(224篇)。当前研究热点主要包括“网络药理学”“代谢组学”“小鼠实验”“苓桂术甘汤”“肠道菌群”“自噬”“炎症”和“专家经验”等。结论:中医药诊疗代谢相关脂肪性肝病已引起学者们的广泛关注。本研究揭示了该领域的研究现状和当前的研究热点,结果有望为该领域的学者开展新研究提供借鉴与参考。


关键词: 代谢相关脂肪性肝病, 非酒精性脂肪性肝病, 中医药, 文献计量学, 知识图谱

Abstract:

Objective: To conduct a quantitative analysis of the current status and hotspots of traditional Chinese medicine TCM research on metabolic dysfunction-associated steatotic liver disease MASLD based on bibliometrics.Methods: Relevant research literature were retrieved from CNKI by the computer with the search timespan from the establishment to June 1 2024. Two researchers independently screened the literature and cross-checked the results to determine the literature included in the analysis. VOSviewer was used to conduct statistical analysis on the annual number of publications provinces authors institutions journals and keywords and corresponding knowledge maps were drawn.Results: A total of 3529 articles published from 1998 to 2024 were included. The annual number of publications generally showed an upward trend. These articles were from 30 provincial-level administrative regions with Shanghai 351 articles and Beijing 316 articleshaving the most publications. Among 1811 institutions universities and their affiliated hospitals specializing in TCM publsihed the most publications with Shuguang Hospital Affiliated to Shanghai University of TCM 128 articles ranked first. Among 7842 authors Zhao Wenxia 69 articles and Li Junxiang 60 articles had the largest number of publications. However the cooperation among different institutions or scholars in this field was not close. Among 385 journals the Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases 224 articles publsihed the most publications. Current research hotspots mainly included network pharmacology”, “metabolomics”, “mouse experiment”, “Linggui Zhugan decoction”, “gut microbiota”, “autophagy”, “inflammation”, and expert experience.Conclusion: TCM treatment for MASLD has attracted wide attention from researchers. This study reveals the research status and current hotspots in this field and the results are expected to provide reference for scholars in this field to carry out new research.

  

Key words: Metabolic dysfunction-associated fatty liver disease , Non-alcoholic fatty liver disease , Traditional Chinese medicine , Bibliometrics , Knowledge mapping

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