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综合内科142例老年人肺栓塞临床特点

马育霞1,刘毅2,王鹏升1,李英1,赵红英1,刘云峰1   

  1. (1河北省沧州市中心医院老年内科,沧州 061001;2河北省沧州监狱医院内科,沧州 061001)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-05-25
  • 基金资助:
    #基金项目:沧州市科技基金项目,①编号:1213056ZD,课题名称wells评分在疑似肺栓塞患者筛选的价值;②编号:131302071,课题名称:不同性别、年龄肺栓塞患者临床症状、相关危险因素研究及诊疗对策。

Risk Factors of Pulmonary Embolism in the Elderly Patients

Ma Yu-xia,Liu Yi,Wang Peng-sheng,et al.   

  1. (1Department of Geriatric Internal Medicine,the Cangzhou Central Hospital,Cangzhou 061001,China; 2Department of Internal Medicine,Hebei Prison Hospital,Cangzhou 061001, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2016-05-25

摘要: 【摘要】目的:总结老年肺栓塞住院病人的临床特点以及抗凝治疗前后D-二聚体的变化。方法:选择我院收治的肺栓塞患者256例,观察组分为老年组142例,非老年组114例,比较临床表现和危险因素差异,同时观察抗凝治疗后血浆D-二聚体含量的变化。并选取健康对照组200例,采用多元Logistic回归模型分析老年人肺栓塞危险因素。结果:观察2组呼吸困难、咳嗽、胸闷的患病率分别是85.2%和81.6%,72.5%和71.1%,57%和62.3%,两组比较无统计学差异,但非老年组咯血的患病率(27.2%),高于老年组(9.9%),差异有统计学意义(P=0.000);老年组无症状(12.7%)多于非老年组(2.6%),有统计学意义(P=0.004)。老年组的危险因素多见于糖尿病、高血压、慢性阻塞肺疾病和既往脑卒中。抗凝治疗后,两组患者D-二聚体均较治疗前明显降低,差异有统计学意义。老年组的独立危险因素分别为COPD、既往深静脉血栓病史、恶性肿瘤和既往脑卒中;非老年组为既往深静脉血栓史。结论:老年人急性肺栓塞的临床表现多不典型,现呼吸困难仍为最常见的临床表现。COPD、恶性肿瘤、既往深静脉血栓和脑卒中均为老年人急性肺栓塞的独立危险因素,需注意加以鉴别。

Abstract: 【ABSTRACT】Objective: To summarize the clinical feature and risk factors of patients suffering from pulmonary embolism(PE) in the elderly patients,and explore the change of D-dimer after anticoagulant therapy.Methods:256 patients with suspected PE were admitted from January 2009 to May 2015 in the Cangzhou Central Hospital,acomparison of clinical features and risk factors,between the elderly groups and non-elderly.The change of D-dimer content was determined before and 3-day after anticoagulant therapy in two groups.Results:The most important risk factor for the elderly patients was stroke.but for non-elderly patients was DVT.After anticoagulant therapy,the decreasing level of D-dimer was significant statistical differences in two groups. Conclusion:Between the elderly and non-elderly groups,the main clinical manifestations were similar.The main symptoms is dyspnea.The risk factors of elderly patients is COPD, therioma, DVT and stroke.After anticoagulant therapy,the content of D-dimer is lower than 3-day ago.D-dimer test is a good screening test for PE. (P<0.05).