Abstract: Objective：To understand status after trabeculectomy in patients with disease related knowledge，provide reference for clinical implementation of health education and the continuation of care.Methods：Using self-designed questionnaire， including general information and disease related knowledge， a total of 52 patients after trabeculectomy for questionnaire.Results：Disease-related knowledge score of 52 patients after trabeculectomy was (13.38±4.47)， each dimension score of intraocular pressure related knowledge， symptoms， treatment， postoperative rehabilitation， disease cause were respectively (3.17±0.41)， (2.53±0.82)， (2.26±0.37)， (2.42±0.56)， (2.81±0.37).Different duration time of patient disease-related knowledge accuracy comparison difference was statistically significant (P<0.05).Conclusion：Patients with diseases after trabeculectomy are lack of relevant knowledge，especially lack of some key knowledge. Clinical and continue nursing should be targeted to strengthen health education，improve the level of cognitive in patients with disease， so as to improve the self-care ability of patients and health management level.