关键词: font-size:medium, ">多潘立酮；药品说明书；用量；警戒

Abstract: Objective： To investigate the current situation of outpatient use of domperidone tablets in our center， based on information technology and artificial intelligence to mine and utilize the knowledge of drug instructions， and by evaluating the dosage of patients in different age groups， so as to provide reference and data for clinical safe and rational drug use. Methods： By collecting the prescriptions of domperidone in our center from March to August in 2019， we analyzed the distribution of all ages groups， prescription dosage and prescription amount， frequency of drug use(DDDs)， drug utilization index (DUI) and average daily cost. With reference to the revised instruction of domperidone tablets and the warning function of the intelligent system， the dosing frequency， dosage， daily dosage， total dosage and using days were evaluated. Results： There were 549 prescriptions for domperidone tablets in the outpatient department， including 217 prescriptions for males and 332 prescriptions for females. The average age was (71.76±12.39) years old. The elderly patients aged from 61 to 90 years old were the majority [78.87% (433/549)]， and the elderly patients aged from 61 to 70 years old ranked first [30.42% (167/549)]. The top three age groups in the DDDs sequence were 61-70 years old females， 71-80 years old females， and 81-90 years old females. The recommended dose according to the drug instruction is 10 mg each oral dose， 3 times/d， and the average daily dose for all age groups is 30 mg. Conclusion： The dosing of domperidone tablets in the outpatient department of our center conforms to the recommendation of the instructions， and the DUI is all 1.00. Since most of the elderly patients in community hospitals are outpatients， the intelligent information system can provide personalized services for patients of all ages， which is conducive to the rationality of domperidone dosage.

Key words: font-size:medium, ">Domperidone； Drug instructions； Dosage；Alert